Carbamic acid, (4-methylphenyl)-, phenylmethyl ester (9CI)

Base Information

• Chemical Name: Carbamic acid, (4-methylphenyl)-, phenylmethyl ester (9CI)
• CAS No.: 7625-64-1
• Molecular Formula: C15H15NO2
• Molecular Weight: 241.29
• Mol file: 7625-64-1.mol

Synonyms:benzyl N-p-tolylcarbamate;Benzyl 4-methylphenylcarbamate;N--carbaminsaeure-benzylester;4-Methyl-carbanilsaeure-benzylester;p-Tolyl-carbamidsaeure-benzylester;benzyl p-tolylcarbamate;p-tolylcarbamic acid benzyl ester;

Chemical Property of Carbamic acid, (4-methylphenyl)-, phenylmethyl ester (9CI)

Chemical Property:

• PSA: 38.33000
• LogP: 3.81670

Purity/Quality:

(4-METHYLPHENYL)CARBAMIC ACID PHENYLMETHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Carbamic acid, (4-methylphenyl)-, phenylmethyl ester (9CI)

There total 15 articles about Carbamic acid, (4-methylphenyl)-, phenylmethyl ester (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

p-toluidine (106-49-0,12221-03-3) + benzyl chloroformate (501-53-1,94274-21-2) → p-tolyl-carbamic acid benzyl ester (7625-64-1)

Guidance literature:

With lanthanum(III) nitrate; at 20 ℃; for 0.0666667h;

DOI:10.1016/j.tetlet.2006.11.015

Reference yield: 91.0%

benzyloxycarbonyl azide (3422-03-5) + 4-methylphenylboronic acid (5720-05-8) → p-tolyl-carbamic acid benzyl ester (7625-64-1)

Guidance literature:

With copper(l) chloride; In methanol; at 20 ℃; for 2h;

DOI:10.1021/jo502828r

Reference yield: 88.0%

N-(Benzyloxycarbonyloxy)succinimide (13139-17-8) + p-toluidine (106-49-0,12221-03-3) → p-tolyl-carbamic acid benzyl ester (7625-64-1)

Guidance literature:

With 1-butyl-3-methylimidazolium Tetrafluoroborate; In neat (no solvent); at 25 ℃; for 0.133333h;

DOI:10.1039/c5ra12121c

upstream raw materials:

p-toluidine

benzyl chloroformate

p-methylazidobenzene

carbon dioxide

Downstream raw materials:

p-Tolylisocyanate

benzyl alcohol

methyl p-tolyl carbamic acid 1-benzyl ester

benzyl ((2-methyloxiran-2-yl)methyl)(p-tolyl)carbamate