Technology Process of Benzonitrile, 4-(2-phenyl-1,3-dioxolan-2-yl)-
There total 1 articles about Benzonitrile, 4-(2-phenyl-1,3-dioxolan-2-yl)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
toluene-4-sulfonic acid;
In
benzene;
Heating;
DOI:10.1021/ja00393a023
- Guidance literature:
-
4-cyanobenzophenone ethylene acetal;
With
lithium aluminium tetrahydride;
In
tetrahydrofuran; benzene;
at 0 - 20 ℃;
for 1.5h;
With
sodium hydroxide; water;
In
tetrahydrofuran; benzene;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 2.)NH4Cl / 1.) ether, benzene, 60 deg C, 5 h, 2.) 80 deg C, 1 h
2: 80 percent / NaOH / ethanol; H2O / 40 h / Ambient temperature
3: 70.5 percent / H2 / 5percent Pd-C / dioxane
4: hydrazine hydrate, NaOH / bis-(2-hydroxy-ethyl) ether / 1.) reflux, 1 h, 2.) 220 deg C, 4 h
5: 2N HCl / 1 h
With
hydrogenchloride; sodium hydroxide; hydrogen; ammonium chloride; hydrazine hydrate;
palladium on activated charcoal;
In
1,4-dioxane; ethanol; water; diethylene glycol;
DOI:10.1021/ja00393a023
