3-{8-[Butyl(methyl)amino]-1,4-dioxaspiro[4.5]decan-8-yl}phenol

Base Information

Chemical Name:3-{8-[Butyl(methyl)amino]-1,4-dioxaspiro[4.5]decan-8-yl}phenol
CAS No.:76626-28-3
Molecular Formula:C₁₉H₂₉NO₃
Molecular Weight:319.444
Hs Code.:
ChEMBL ID:CHEMBL326573
DSSTox Substance ID:DTXSID40506738
Wikidata:Q82362625

Synonyms:76626-28-3;CHEMBL326573;DTXSID40506738;3-{8-[Butyl(methyl)amino]-1,4-dioxaspiro[4.5]decan-8-yl}phenol

Suppliers and Price of 3-{8-[Butyl(methyl)amino]-1,4-dioxaspiro[4.5]decan-8-yl}phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 3-{8-[Butyl(methyl)amino]-1,4-dioxaspiro[4.5]decan-8-yl}phenol

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:319.21474379
Heavy Atom Count:23
Complexity:371

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCN(C)C1(CCC2(CC1)OCCO2)C3=CC(=CC=C3)O

Technology Process of 3-{8-[Butyl(methyl)amino]-1,4-dioxaspiro[4.5]decan-8-yl}phenol

There total 5 articles about 3-{8-[Butyl(methyl)amino]-1,4-dioxaspiro[4.5]decan-8-yl}phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 22428-87-1
4,4-ethylenedioxycyclohexan-1-ol

: 76626-28-3
4-(m-hydroxyphenyl)-4-(n-butylmethylamino)cyclohexanone ethylene ketal

Guidance literature:: Multi-step reaction with 3 steps

1: 2.5 N aq. HCl / methanol / 48 h / Ambient temperature

2: 1.) Mg / 1.) THF, 2.) THF, reflux, 24 h

3: etheral HCl

With hydrogenchloride; magnesium; In methanol;
DOI:10.1021/jm00135a019

Reference yield:

: 88642-64-2
Butyl-methyl-{8-[3-(tetrahydro-pyran-2-yloxy)-phenyl]-1,4-dioxa-spiro[4.5]dec-8-yl}-amine

: 76626-28-3
4-(m-hydroxyphenyl)-4-(n-butylmethylamino)cyclohexanone ethylene ketal

Guidance literature:: With hydrogenchloride;
DOI:10.1021/jm00135a019

Reference yield:

: 57999-49-2
3-(tetrahydropyran-2-yloxy)phenyl bromide

: 76626-28-3
4-(m-hydroxyphenyl)-4-(n-butylmethylamino)cyclohexanone ethylene ketal

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) Mg / 1.) THF, 2.) THF, reflux, 24 h

2: etheral HCl

With hydrogenchloride; magnesium;
DOI:10.1021/jm00135a019