(2E)-2-cyano-3-[5-(2-methyl-4-nitrophenyl)furan-2-yl]-N-(2-methylphenyl)prop-2-enamide

Base Information

Chemical Name:(2E)-2-cyano-3-[5-(2-methyl-4-nitrophenyl)furan-2-yl]-N-(2-methylphenyl)prop-2-enamide
CAS No.:5909-47-7
Molecular Formula:C22H17N3O4
Molecular Weight:277.236
Hs Code.:
DSSTox Substance ID:DTXSID20416684
Wikidata:Q82226133

Synonyms:STK179426;(2E)-2-cyano-3-[5-(2-methyl-4-nitrophenyl)furan-2-yl]-N-(2-methylphenyl)prop-2-enamide;5909-47-7;DTXSID20416684;AKOS000323109

Suppliers and Price of (2E)-2-cyano-3-[5-(2-methyl-4-nitrophenyl)furan-2-yl]-N-(2-methylphenyl)prop-2-enamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 0 raw suppliers

Chemical Property of (2E)-2-cyano-3-[5-(2-methyl-4-nitrophenyl)furan-2-yl]-N-(2-methylphenyl)prop-2-enamide

Chemical Property:

Vapor Pressure:2.35E-15mmHg at 25°C
Boiling Point:621.2°Cat760mmHg
Flash Point:329.5°C
Density:1.319g/cm³
XLogP3:5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:387.12190603
Heavy Atom Count:29
Complexity:692

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1NC(=O)C(=CC2=CC=C(O2)C3=C(C=C(C=C3)[N+](=O)[O-])C)C#N
Isomeric SMILES:CC1=CC=CC=C1NC(=O)/C(=C/C2=CC=C(O2)C3=C(C=C(C=C3)[N+](=O)[O-])C)/C#N

Technology Process of (2E)-2-cyano-3-[5-(2-methyl-4-nitrophenyl)furan-2-yl]-N-(2-methylphenyl)prop-2-enamide

There total 5 articles about (2E)-2-cyano-3-[5-(2-methyl-4-nitrophenyl)furan-2-yl]-N-(2-methylphenyl)prop-2-enamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 67-52-7,944357-77-1
BARBITURIC ACID

: 5153-67-3
nitrostyrene

: 5909-47-7
6-hydroxy-5-(2-nitro-1-phenylethyl)pyrimidine-2,4(1H,3H)-dione

Guidance literature:: With water; diethylamine; at 20 ℃; for 1h; Green chemistry;
DOI:10.3390/molecules19011150

Reference yield:

: 5153-67-3
nitrostyrene

: 5909-47-7
5-(2-nitro-1-phenyl-ethyl)-pyrimidine-2,4,6-trione

Guidance literature:: With methanol;
DOI:10.1021/ja01623a064

Reference yield:

: 100-52-7
benzaldehyde

: 5909-47-7
6-hydroxy-5-(2-nitro-1-phenylethyl)pyrimidine-2,4(1H,3H)-dione

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / ethanol / 1 h / 20 °C

2: diethylamine; water / 1 h / 20 °C / Green chemistry

With water; diethylamine; sodium hydroxide; In ethanol; 2: |Michael Addition;
DOI:10.3390/molecules19011150