2-Ethynyltetrahydro-2h-pyran

Base Information

Chemical Name:2-Ethynyltetrahydro-2h-pyran
CAS No.:76928-53-5
Molecular Formula:C7H10O
Molecular Weight:110.156
Hs Code.:
European Community (EC) Number:824-413-8
DSSTox Substance ID:DTXSID10478897
Nikkaji Number:J554.327D

Synonyms:2-ethynyloxane;2-ethynyltetrahydro-2h-pyran;76928-53-5;2H-Pyran, 2-ethynyltetrahydro-;2-ethynyltetrahydropyran;SCHEMBL236882;DTXSID10478897;ZKTKNSXLODIMFZ-UHFFFAOYSA-N;MFCD29046558;AKOS026716051;AT10034;PS-20321;CS-0216262;EN300-373991;F2147-2842

Suppliers and Price of 2-Ethynyltetrahydro-2h-pyran

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2-Ethynyltetrahydro-2h-pyran

Chemical Property:

Vapor Pressure:8.501mmHg at 25°C
XLogP3:1.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:110.073164938
Heavy Atom Count:8
Complexity:109

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C#CC1CCCCO1

Technology Process of 2-Ethynyltetrahydro-2h-pyran

There total 12 articles about 2-Ethynyltetrahydro-2h-pyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 57365-55-6
hept-6-yne-1,5-diol

: 76928-53-5
(+/-)-2-cyanoterahydropyran

Guidance literature:: With ammonium tetrafluoroborate; [(Cp^*)RuCl(SMe)]2; In 1,2-dichloro-ethane; at 60 ℃; for 1h;
DOI:10.1002/chem.200400833

Reference yield:

: 202604-25-9
(+/-)-2-(2-trimethylsilylethynyl)tetrahydropyran

: 76928-53-5
(+/-)-2-cyanoterahydropyran

Guidance literature:: With potassium carbonate; In methanol; at 20 ℃; for 1h;
DOI:10.1016/S0040-4020(97)10357-X

Reference yield:

: 110-87-2
3,4-dihydro-2H-pyran

: 76928-53-5
(+/-)-2-cyanoterahydropyran

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / HCl / diethyl ether / 8 h

2: 1.) C₂H₅MgBr / 1.) THF, 25 - 30 deg C, 6.5 h, 2.) (C₂H₅)2O, THF, room temp., overnight

With hydrogenchloride; ethylmagnesium bromide; In diethyl ether;
DOI:10.1021/jo00071a015