1-(4-Fluorophenyl)-3-pyridin-4-ylurea

Base Information

Chemical Name:1-(4-Fluorophenyl)-3-pyridin-4-ylurea
CAS No.:76947-67-6
Molecular Formula:C12H10FN3O
Molecular Weight:231.22600
Hs Code.:
ChEMBL ID:CHEMBL168337
DSSTox Substance ID:DTXSID20589468
Nikkaji Number:J273.804J
Wikidata:Q82482854
Mol file:76947-67-6.mol

Synonyms:1-(4-fluorophenyl)-3-pyridin-4-ylurea;MLS001230225;SMR000678209;76947-67-6;HMS2991O04;CHEMBL168337;SCHEMBL4917143;BDBM96790;DTXSID20589468;cid_17262955;STK493919;AKOS003346333;1-(4-fluorophenyl)-3-(4-pyridyl)urea;N-(4-Fluorophenyl)-N'-pyridin-4-ylurea;1-(4-fluorophenyl)-3-pyridin-4-yl-urea;SR-01000832969;SR-01000832969-2

Suppliers and Price of 1-(4-Fluorophenyl)-3-pyridin-4-ylurea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1-(4-Fluorophenyl)-3-pyridin-4-ylurea

Chemical Property:

PSA：57.25000
LogP:2.35960
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:231.08079011
Heavy Atom Count:17
Complexity:248

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1NC(=O)NC2=CC=NC=C2)F

Technology Process of 1-(4-Fluorophenyl)-3-pyridin-4-ylurea

There total 3 articles about 1-(4-Fluorophenyl)-3-pyridin-4-ylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 504-24-5
4-aminopyridine

: 1195-45-5
para-fluorophenyl isocyanate

: 76947-67-6
N-4-fluorophenyl-N'-4-pyridylurea

Guidance literature:: In tetrahydrofuran;
DOI:10.1021/jm00164a061

Reference yield:

: 54-85-3,7640-37-1
isoniazid

: 371-40-4
4-fluoroaniline

: 76947-67-6
N-4-fluorophenyl-N'-4-pyridylurea

Guidance literature:: isoniazid; With hydrogenchloride; water; sodium nitrite; at 0 - 5 ℃; for 1h;

4-fluoroaniline; Reflux;
DOI:10.1016/j.molstruc.2010.01.030