Benzyl 2-benzamidoethylcarbamate

Base Information

Chemical Name:Benzyl 2-benzamidoethylcarbamate
CAS No.:77153-06-1
Molecular Formula:C17H18N2O3
Molecular Weight:298.342
Hs Code.:
DSSTox Substance ID:DTXSID101241581

Synonyms:benzyl 2-benzamidoethylcarbamate;DTXSID101241581;77153-06-1;Phenylmethyl N-[2-(benzoylamino)ethyl]carbamate

Suppliers and Price of Benzyl 2-benzamidoethylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzyl 2-benzamidoethylcarbamate

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:7
Exact Mass:298.13174244
Heavy Atom Count:22
Complexity:348

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC(=O)NCCNC(=O)C2=CC=CC=C2

Technology Process of Benzyl 2-benzamidoethylcarbamate

There total 5 articles about Benzyl 2-benzamidoethylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 72080-83-2
2-benzyloxycarbonylaminoethylamine

: 98-88-4
benzoyl chloride

: 77153-06-1
N-benzoyl-N'-<(benzyloxy)carbonyl>ethylenediamine

Guidance literature:: With triethylamine; In diethyl ether;
DOI:10.1021/jo00325a006

Reference yield:

: 77987-49-6
benzyl 2-hydroxyethylcarbamate

: 77153-06-1
N-benzoyl-N'-<(benzyloxy)carbonyl>ethylenediamine

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine / dichloromethane / 1.5 h / 0 °C

2: sodium azide / dimethyl sulfoxide / 2 h / 70 °C

3: triphenylphosphine / methanol; water / 2 h / Reflux

4: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / N,N-dimethyl-formamide / 8 h / 80 °C

With sodium azide; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; triphenylphosphine; In methanol; dichloromethane; water; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2011.08.024

Reference yield:

: 134307-72-5
2-(((benzyloxy)carbonyl)amino)ethyl 1-methanesulfonate

: 77153-06-1
N-benzoyl-N'-<(benzyloxy)carbonyl>ethylenediamine

Guidance literature:: Multi-step reaction with 3 steps

1: sodium azide / dimethyl sulfoxide / 2 h / 70 °C

2: triphenylphosphine / methanol; water / 2 h / Reflux

3: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / N,N-dimethyl-formamide / 8 h / 80 °C

With sodium azide; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; triphenylphosphine; In methanol; water; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2011.08.024