Nickel, bis(1-(nitroso-kappaN)-2-naphthalenolato-kappaO)-, (T-4)-

Base Information

• Chemical Name: Nickel, bis(1-(nitroso-kappaN)-2-naphthalenolato-kappaO)-, (T-4)-
• CAS No.: 14406-66-7
• Molecular Formula: C₆H₁₀ClNO₂
• Molecular Weight: 163.604
• European Community (EC) Number: 238-380-7
• Mol file: 14406-66-7.mol

Synonyms:EINECS 238-380-7;14406-66-7;Nickel, bis(1-(nitroso-kappaN)-2-naphthalenolato-kappaO)-, (T-4)-;Bis(1-nitrosonaphthalen-2-olato-N1,O2)nickel;Nickel, bis[1-(nitroso-.kappa.N)-2-naphthalenolato-.kappa.O]-, (T-4)-;C20H12N2NiO4;C20-H12-N2-Ni-O4;Nickel, bis(1-nitroso-2-naphthalenolato-N,O2)-, (T-4)-;Nickel, bis(1-nitroso-2-naphthalenolato-N1,O2)-, (T-4)-

Chemical Property of Nickel, bis(1-(nitroso-kappaN)-2-naphthalenolato-kappaO)-, (T-4)-

Chemical Property:

• Vapor Pressure: 1.31E-05mmHg at 25°C
• Boiling Point: 357.6°Cat760mmHg
• Flash Point: 170.1°C
• PSA: 104.98000
• Density: g/cm³
• LogP: 6.76300
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 0
• Exact Mass: 402.015049
• Heavy Atom Count: 27
• Complexity: 195

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=CC(=C2N=O)[O-].C1=CC=C2C(=C1)C=CC(=C2N=O)[O-].[Ni+2]

Technology Process of Nickel, bis(1-(nitroso-kappaN)-2-naphthalenolato-kappaO)-, (T-4)-

There total 11 articles about Nickel, bis(1-(nitroso-kappaN)-2-naphthalenolato-kappaO)-, (T-4)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

morpholine (110-91-8,99108-56-2) + chloroacetyl chloride (79-04-9) → N-chloroacetylmorpholine (1440-61-5)

Guidance literature:

With potassium carbonate; In toluene; at 60 ℃; for 2h;

Reference yield: 95.0%

morpholine (110-91-8,99108-56-2) + Chloroacetic anhydride (541-88-8) → N-chloroacetylmorpholine (1440-61-5)

Guidance literature:

In chloroform; at 20 ℃; for 1h;

DOI:10.1016/j.bmc.2017.02.009

Reference yield: 60.0%

→ N-chloroacetylmorpholine (1440-61-5)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃;

upstream raw materials:

morpholine

chloroacetyl bromide

chloroacetyl chloride

Trichloroethylene

Refernces

• 1、 Dovala, Dustin,Fischer, Christian,Nomura, Daniel K.,Peitsinis, Zisis,Spradlin, Jessica N.,Trauner, Dirk,Yang, Chao,Zhang, Yingkai,Rühmann, Klaus-Peter,Vep?ek, Nynke A.. "De novo Design of SARS-CoV-2 Main Protease Inhibitors". supporting information. . Retrieved 2021/10/16.
• 2、 Prinsloo, Izak F.,Zuma, Nonkululeko H.,Aucamp, Janine,N’Da, David D.. "Synthesis and in vitro antileishmanial efficacy of novel quinazolinone derivatives". . p. 383 - 398. Retrieved 2020/09/23.