3,6,9,12,15-Pentaoxaheptadecanedioic acid

Base Information

Chemical Name:3,6,9,12,15-Pentaoxaheptadecanedioic acid
CAS No.:77855-75-5
Molecular Formula:C12H22O9
Molecular Weight:310.301
Hs Code.:
DSSTox Substance ID:DTXSID00431678
Nikkaji Number:J1.973.045J
Mol file:77855-75-5.mol

Synonyms:77855-75-5;3,6,9,12,15-Pentaoxaheptadecanedioic acid;PEG5-(CH2CO2H)2;HOOCCH2O-PEG4-CH2COOH;3,6,9,12,15-Pentaoxaheptadecane-1,17-dioic acid;MFCD29079379;CH2COOH-PEG5-CH2COOH;bis PEG5 acetic acid;Bis-PEG5-acetic acid;2-[2-[2-[2-[2-(carboxymethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic Acid;SCHEMBL6666413;DTXSID00431678;CDA85575;AS-65074;BP-23126;SY251168;HY-124780;CS-0087653;C70494;A904048;2,2'-[Oxybis(ethyleneoxyethyleneoxy)]diacetic acid;3,6,9,12,15-Pentaoxaheptadecane-1,17-dioicacid

Suppliers and Price of 3,6,9,12,15-Pentaoxaheptadecanedioic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

BroadPharm
PEG5-(CH2CO2H)2 98%
1 G
$ 780.00

BroadPharm
PEG5-(CH2CO2H)2 98%
500 MG
$ 480.00

BroadPharm
PEG5-(CH2CO2H)2 98%
250 MG
$ 350.00

BroadPharm
PEG5-(CH2CO2H)2 98%
5 G
$ 1900.00

Activate Scientific
HOOCCH2O-PEG4-CH2COOH 95+%
5 g
$ 1338.00

Acrotein
HOOCCH2O-PEG4-CH2COOH 97%
0.5g
$ 183.34

Total 10 raw suppliers

Chemical Property of 3,6,9,12,15-Pentaoxaheptadecanedioic acid

Chemical Property:

Boiling Point:495.8±40.0 °C(Predicted)
PKA:3.09±0.10(Predicted)
PSA：120.75000
Density:1.252±0.06 g/cm3(Predicted)
LogP:-0.76140
Solubility.:Soluble in Water, DMSO, DMF
XLogP3:-1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:16
Exact Mass:310.12638228
Heavy Atom Count:21
Complexity:244

Purity/Quality:

97% ^*data from raw suppliers

PEG5-(CH2CO2H)2 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(COCCOCC(=O)O)OCCOCCOCC(=O)O
Description PEG5-(CH2CO2H)2 is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Technology Process of 3,6,9,12,15-Pentaoxaheptadecanedioic acid

There total 3 articles about 3,6,9,12,15-Pentaoxaheptadecanedioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 211746-78-0
di-tert-butyl 3,6,9,12,15-pentaoxaheptadecanedioate

: 77855-75-5,39927-08-7
3,6,9,12,15-pentaoxaheptadecanedioic acid

Guidance literature:: With trifluoroacetic acid; In dichloromethane; for 1h; Ambient temperature;
DOI:10.1021/jo980350s

Reference yield:

: 112-60-7
Tetraethylene glycol

: 77855-75-5,39927-08-7
3,6,9,12,15-pentaoxaheptadecanedioic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 35 percent / aq. NaOH, Bu₄NHSO₄ / toluene / 1.) 0 deg C, 10 min, 2.) room temp., 30 min

2: 100 percent / CF₃COOH / CH₂Cl₂ / 1 h / Ambient temperature

With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; trifluoroacetic acid; In dichloromethane; toluene;
DOI:10.1021/jo980350s