Ethanone, 2-(4-fluorophenyl)-1-(4-piperidinyl)-

Base Information

Chemical Name:Ethanone, 2-(4-fluorophenyl)-1-(4-piperidinyl)-
CAS No.:78056-85-6
Molecular Formula:C13H16FNO
Molecular Weight:221.275
Hs Code.:
DSSTox Substance ID:DTXSID30434536
Wikidata:Q82248987

Synonyms:Ethanone, 2-(4-fluorophenyl)-1-(4-piperidinyl)-;78056-85-6;SCHEMBL3953274;DTXSID30434536

Suppliers and Price of Ethanone, 2-(4-fluorophenyl)-1-(4-piperidinyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Ethanone, 2-(4-fluorophenyl)-1-(4-piperidinyl)-

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:221.121592296
Heavy Atom Count:16
Complexity:230

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNCCC1C(=O)CC2=CC=C(C=C2)F

Technology Process of Ethanone, 2-(4-fluorophenyl)-1-(4-piperidinyl)-

There total 1 articles about Ethanone, 2-(4-fluorophenyl)-1-(4-piperidinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1-(1-Benzyl-piperidin-4-yl)-2-(4-fluoro-phenyl)-ethanone; compound with (Z)-but-2-enedioic acid

: 78056-85-6
2-(4-Fluoro-phenyl)-1-piperidin-4-yl-ethanone

Guidance literature:: With ammonium formate; palladium on activated charcoal; In methanol; for 0.75h; Heating;
DOI:10.1021/jm00101a012

Reference yield:

: 78056-85-6
2-(4-Fluoro-phenyl)-1-piperidin-4-yl-ethanone

: 1-[4-(4-fluorophenyl)-4-oxobutyl]-4-[2-(4-fluorophenyl)-1-oxoethyl]piperidine

Guidance literature:: Multi-step reaction with 2 steps

1: 195 mg / K₂CO₃, KI / acetonitrile / 24 h / Heating

2: 6 percent / 3N aq. HCl / ethanol / 24 h

With hydrogenchloride; potassium carbonate; potassium iodide; In ethanol; acetonitrile;
DOI:10.1021/jm00101a012