2-(4-Methyl-benzyl)-piperidine hydrochloride

Base Information

Chemical Name:2-(4-Methyl-benzyl)-piperidine hydrochloride
CAS No.:782504-65-8
Molecular Formula:C₁₃H₁₉N*ClH
Molecular Weight:225.762
Hs Code.:2933399990
DSSTox Substance ID:DTXSID50588843
Mol file:782504-65-8.mol

Synonyms:2-(4-Methyl-benzyl)-piperidine hydrochloride;782504-65-8;2-(4-methylbenzyl)piperidine hydrochloride;2-[(4-methylphenyl)methyl]piperidine;hydrochloride;2-[(4-METHYLPHENYL)METHYL]PIPERIDINE HYDROCHLORIDE;DTXSID50588843;MFCD08669734;AB46071;2-(4-methylbenzyl)piperidinehydrochloride;CS-0364596;2-[(4-Methylphenyl)methyl]piperidine--hydrogen chloride (1/1)

Suppliers and Price of 2-(4-Methyl-benzyl)-piperidine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(4-Methyl-benzyl)-piperidineHydrochloride
100mg
$ 65.00

SynQuest Laboratories
2-(4-Methylbenzyl)piperidinehydrochloride
1 g
$ 272.00

American Custom Chemicals Corporation
2-(4-METHYL-BENZYL)-PIPERIDINE HYDROCHLORIDE 95.00%
5MG
$ 501.42

Total 4 raw suppliers

Chemical Property of 2-(4-Methyl-benzyl)-piperidine hydrochloride

Chemical Property:

Vapor Pressure:0.000211mmHg at 25°C
Boiling Point:321.9oC at 760 mmHg
Flash Point:148.5oC
PSA：12.03000
LogP:3.81040
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:225.1284273
Heavy Atom Count:15
Complexity:159

Purity/Quality:

98%min ^*data from raw suppliers

2-(4-Methyl-benzyl)-piperidineHydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)CC2CCCCN2.Cl

Technology Process of 2-(4-Methyl-benzyl)-piperidine hydrochloride

There total 4 articles about 2-(4-Methyl-benzyl)-piperidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 29335-87-3
2-(4-methyl-benzyl)-pyridine

: 782504-65-8
2-[(4-methylphenyl)methyl]piperidine hydrochloride

Guidance literature:: With hydrogen; palladium on activated charcoal; In acetic acid; at 65 ℃; under 7500.75 Torr;
DOI:10.1002/ejoc.200400215

Reference yield:

: 1121-60-4
pyridine-2-carbaldehyde

: 782504-65-8
2-[(4-methylphenyl)methyl]piperidine hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 89 percent / tetrahydrofuran / 10 h / 20 °C

2: 87 percent / H₂; H₂SO₄ / Pd/C / methanol / 25 °C / 750.08 Torr

3: 82 percent / H₂ / Pd/C / acetic acid / 65 °C / 7500.75 Torr

With sulfuric acid; hydrogen; palladium on activated charcoal; In tetrahydrofuran; methanol; acetic acid;
DOI:10.1002/ejoc.200400215

Reference yield:

: 29263-67-0,125141-76-6,125226-24-6
α-(4-methylphenyl)-2-pyridinemethanol

: 782504-65-8
2-[(4-methylphenyl)methyl]piperidine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / H₂; H₂SO₄ / Pd/C / methanol / 25 °C / 750.08 Torr

2: 82 percent / H₂ / Pd/C / acetic acid / 65 °C / 7500.75 Torr

With sulfuric acid; hydrogen; palladium on activated charcoal; In methanol; acetic acid;
DOI:10.1002/ejoc.200400215