Benzenesulfonamide, 4-methyl-N-(1-methyl-2-propenyl)-

Base Information

• Chemical Name: Benzenesulfonamide, 4-methyl-N-(1-methyl-2-propenyl)-
• CAS No.: 78388-18-8
• Molecular Formula: C11H15NO2S
• Molecular Weight: 225.312
• DSSTox Substance ID: DTXSID70452633
• Nikkaji Number: J274.710C
• Mol file: 78388-18-8.mol

Synonyms:78388-18-8;Benzenesulfonamide, 4-methyl-N-(1-methyl-2-propenyl)-;DTXSID70452633;N-(1-Methylallyl)-p-toluenesulfonamide

Chemical Property of Benzenesulfonamide, 4-methyl-N-(1-methyl-2-propenyl)-

Chemical Property:

• XLogP3: 2.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 225.08234989
• Heavy Atom Count: 15
• Complexity: 297

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)NC(C)C=C

Technology Process of Benzenesulfonamide, 4-methyl-N-(1-methyl-2-propenyl)-

There total 23 articles about Benzenesulfonamide, 4-methyl-N-(1-methyl-2-propenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

N-(1-methylallyl)-N-(tert-butoxycarbonyl)-p-toluenesulfonamide (1446670-96-7) → N-(1-methyl-allyl)-4-methyl-benzenesulfonamide (78388-18-8)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 24h;

DOI:10.1002/ejoc.201300375

Reference yield: 96.0%

O-[but-(2Z)-enyl]tosylcarbamate → N-(1-methyl-allyl)-4-methyl-benzenesulfonamide (78388-18-8)

Guidance literature:

With lithium bromide; palladium diacetate; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1021/ol006130u

Reference yield: 92.0%

O-but-2-en-1-yl N-tosylcarbamate (612035-98-0) → N-(1-methyl-allyl)-4-methyl-benzenesulfonamide (78388-18-8)

Guidance literature:

With silver trifluoromethanesulfonate; N-ethyl-N,N-diisopropylamine; gold(I) chloride; In water; at 75 ℃; for 3h; regioselective reaction;

DOI:10.1021/ol100056f

upstream raw materials:

vinyl magnesium bromide

acetaldehyde

N-sulfinyl-p-toluenesulfonamide

N-tert-Butylsulfanyl-4-methyl-N-(1-methyl-allyl)-benzenesulfonamide

Downstream raw materials:

2-methyl-1-(4-methylbenzenesulfonyl)-1H-pyrrole

N-(but-3-en-2-yl)-4-methyl-N-(phenylethynyl)benzenesulfonamide

N-(but-3-en-2-yl)-2-oxo-2-phenyl-N-tosylacetamide

4-methyl-N-[(2E)-1-methyl-3-phenyl-2-propen-1-yl]benzenesulfonamide