Vinylmagnesium bromide

Base Information

• Chemical Name: Vinylmagnesium bromide
• CAS No.: 1826-67-1
• Molecular Formula: C2H3BrMg
• Molecular Weight: 131.255
• Hs Code.: 29319090
• Mol file: 1826-67-1.mol

Synonyms:Magnesium,bromovinyl- (7CI,8CI);Vinylmagnesium bromide (6CI);Bromovinylmagnesium;Ethenylmagnesium bromide;Norman reagent;

Chemical Property of Vinylmagnesium bromide

Chemical Property:

• Appearance/Colour: Clear light brown to brown solution
• Flash Point: -17 °C
• PSA: 0.00000
• Density: 0.981 g/mL at 25 °C
• LogP: 1.52480
• Storage Temp.: Refrigerator
• Solubility.: vigorous reaction
• Water Solubility.: vigorous reaction

Purity/Quality:

99% ^*data from raw suppliers

Vinylmagnesium Bromide (14% in Tetrahydrofuran, ca. 1mol/L) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F, C
• Hazard Codes: F,C
• Statements: 11-14-19-34-14/15-40-37
• Safety Statements: 16-26-29-33-36/37/39-45-6A-43B-43

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Vinylmagnesium bromide solution (1 M in THF) may be used in the synthesis of 2-vinylchroman-4-ones by the conjugate addition with chromones in the presence of a Lewis acid.It may also be used in the following transformations: (S)-3-(benzyloxy)-4-oxo-butanoic acid methyl ester to methyl (3S,4S)-4-hydroxy-3-(phenylmethoxy)hex-5-enoate.(R)-1-Azido-5,6-epoxyhexane to (S)-1-(4-azidobutyl)-2-propen-1-ol.2,3-O-Isopropylidene-D-ribose to 1-[(4R,5S)-5-((1S)-1-hydroxyallyl)-2,2-dimethyl[1,3]dioxolan-4-yl]ethane-1,2-diol.(4S,5S)-2,2-Dimethyl-5-vinyl[1,3]dioxolane-4-carbaldehyde to (1R,4R,5S)- and (1S,4R,5S)-1-(2,2-dimethyl-5-vinyl[1,3]dioxolan-4-yl)prop-2-en-1-ol.Ethyl levulinate to ?-methyl-?-vinylbutyrolactone.

Technology Process of Vinylmagnesium bromide

There total 4 articles about Vinylmagnesium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Vinyl bromide (593-60-2,25951-54-6) → vinyl magnesium bromide (1826-67-1)

Guidance literature:

With magnesium; In tetrahydrofuran; diethyl ether; at 0 ℃;

Reference yield:

Vinyl bromide (593-60-2,25951-54-6) → vinyl magnesium bromide (1826-67-1)

Guidance literature:

In tetrahydrofuran;

DOI:10.1016/S0040-4020(01)91303-1

Reference yield:

→ vinyl magnesium bromide (1826-67-1)

Guidance literature:

DOI:10.1021/jo01082a628

upstream raw materials:

Vinyl bromide

Downstream raw materials:

homoalylic alcohol

allyl alcohol

ethenyltrimethylsilane

3,7-dimethylocta-1,6-dien-3-ol

Refernces

• 1、 Rao, Maddimsetti Venkateswara,Naresh, Annavareddi,Saketh, Gudipati,Rao, Batchu Venkateswara. "Formal synthesis of dysiherbaine". supporting information. p. 6931 - 6933. Retrieved 2019/04/10.
• 2、 -. "Synthesis of coenzyme Q10, ubiquinone". . . Retrieved 2008/06/13.