Benzenesulfonamide, 4-methyl-N-(3-methyl-2-butenyl)-

Base Information

• Chemical Name: Benzenesulfonamide, 4-methyl-N-(3-methyl-2-butenyl)-
• CAS No.: 78388-19-9
• Molecular Formula: C12H17NO2S
• Molecular Weight: 239.338
• Mol file: 78388-19-9.mol

Synonyms:4-methyl-N-(3-methylbut-2-enyl)benzenesulfonamide;N-(3-methyl-2-butenyl)-p-toluenesulfonamide;4-methyl-N-(3-methylbut-2-en-1-yl)benzenesulfonamide;4-methyl-N-(3-methylbut-2 enyl)benzenesulfonamide;N-(3-Methylbut-2-enyl)toluene-p-sulfonamide;

Chemical Property of Benzenesulfonamide, 4-methyl-N-(3-methyl-2-butenyl)-

Chemical Property:

• PSA: 54.55000
• LogP: 3.71120

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenesulfonamide, 4-methyl-N-(3-methyl-2-butenyl)-

There total 21 articles about Benzenesulfonamide, 4-methyl-N-(3-methyl-2-butenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-Boc-N-(3-methylbut-2-enyl)-p-toluenesulfonamide (126745-59-3) → 4-methyl-N-(3-methylbut-2-enyl)benzenesulfonamide (78388-19-9)

Guidance literature:

With trifluoroacetic acid; In chloroform; at 20 ℃; for 0.5h;

DOI:10.3762/bjoc.14.250

Reference yield: 93.0%

O-2-methylbut-3-en-2-yl N-tosylcarbamate (139951-62-5) → 4-methyl-N-(3-methylbut-2-enyl)benzenesulfonamide (78388-19-9)

Guidance literature:

With silver trifluoromethanesulfonate; N-ethyl-N,N-diisopropylamine; gold(I) chloride; In water; at 75 ℃; for 2h; regioselective reaction;

DOI:10.1021/ol100056f

Reference yield: 75.0%

toluene-4-sulfonamide (70-55-3) + prenyl bromide (870-63-3) → 4-methyl-N-(3-methylbut-2-enyl)benzenesulfonamide (78388-19-9)

Guidance literature:

With potassium carbonate; In acetonitrile; at 60 ℃; for 16h;

DOI:10.1021/acs.orglett.0c02116

upstream raw materials:

3-methylbut-2-enyl acetate

sodium p-toluenesulfonamide

toluene-4-sulfonamide

prenyl bromide

Downstream raw materials:

N-prenyl-N-propargyltosylamide

2-ethoxy-4-isopropenyl-1-tosylpyrrolidine

N-bromoacetyl-N-(3-methylbut-2-enyl)toluene-p-sulfonamide

N-but-3-ynyl-4-methyl-N-(3-methyl-but-2-enyl)-benzenesulfonamide