Welcome to LookChem.com Sign In|Join Free
  • or

Encyclopedia

P-Toluenesulfonamide

Base Information Edit
  • Chemical Name:P-Toluenesulfonamide
  • CAS No.:70-55-3
  • Molecular Formula:C7H9NO2S
  • Molecular Weight:171.22
  • Hs Code.:2935.00
  • European Community (EC) Number:200-741-1
  • ICSC Number:1557
  • NSC Number:9908
  • UNII:I8266RI90M
  • DSSTox Substance ID:DTXSID8029105
  • Nikkaji Number:J4.878J
  • Wikidata:Q23013959
  • NCI Thesaurus Code:C156702
  • Pharos Ligand ID:YV1HMSJ2FPKH
  • Metabolomics Workbench ID:54978
  • ChEMBL ID:CHEMBL574
  • Mol file:70-55-3.mol
P-Toluenesulfonamide

Synonyms:4-methylbenzenesulfonamide;4-toluenesulfonamide;4-toluenesulfonamide hydrochloride;4-toluenesulfonamide, 6-(14)C-labeled;4-toluenesulfonamide, mercury (+2) salt (1:1);4-toluenesulfonamide, mercury (+2) salt (2:1);4-toluenesulfonamide, monopotassium salt;4-toluenesulfonamide, monosilver salt;4-toluenesulfonamide, monosodium salt;4-toluenesulfonylamide;para-toluenesulfonamide;para-toluenesulphonamide

Suppliers and Price of P-Toluenesulfonamide
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • 4-Tolylsulfonamide
  • 100g
  • $ 185.00
  • TCI Chemical
  • p-Toluenesulfonamide >98.0%(HPLC)(N)
  • 25g
  • $ 17.00
  • TCI Chemical
  • p-Toluenesulfonamide >98.0%(HPLC)(N)
  • 500g
  • $ 31.00
  • SynQuest Laboratories
  • p-Toluenesulfonamide 98%
  • 2.5 kg
  • $ 167.00
  • SynQuest Laboratories
  • p-Toluenesulfonamide 98%
  • 10 kg
  • $ 628.00
  • SynQuest Laboratories
  • p-Toluenesulfonamide 98%
  • 500 g
  • $ 80.00
  • Sigma-Aldrich
  • p-Toluenesulfonamide reagent grade, 98%
  • 250g
  • $ 25.10
  • Sigma-Aldrich
  • p-Toluenesulfonamide ReagentPlus , ≥99%
  • 10g
  • $ 28.70
  • Sigma-Aldrich
  • 4-Toluenesulfonamide
  • 8082300100
  • $ 20.60
  • Sigma-Aldrich
  • 4-Toluenesulfonamide for synthesis
  • 100 g
  • $ 19.70
Total 214 raw suppliers
Chemical Property of P-Toluenesulfonamide Edit
Chemical Property:
  • Appearance/Colour:White crystalline powder 
  • Vapor Pressure:0.000285mmHg at 25°C 
  • Melting Point:134-137 °C(lit.) 
  • Refractive Index:1.564 
  • Boiling Point:322.2 °C at 760 mmHg 
  • PKA:10.20±0.10(Predicted) 
  • Flash Point:148.6 °C 
  • PSA:68.54000 
  • Density:1.271 g/cm3  
  • LogP:2.42350 
  • Storage Temp.:Store below +30°C. 
  • Solubility.:DMSO: soluble 
  • Water Solubility.:0.32 g/100 mL (25 º C) 
  • XLogP3:0.8
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:3
  • Rotatable Bond Count:1
  • Exact Mass:171.03539970
  • Heavy Atom Count:11
  • Complexity:209
Purity/Quality:

99% min *data from raw suppliers

4-Tolylsulfonamide *data from reagent suppliers

Safty Information:
  • Pictogram(s): HarmfulXn, IrritantXi 
  • Hazard Codes:Xi,Xn 
  • Statements: 36-20/21/22 
  • Safety Statements: 26-36 
MSDS Files:

SDS file from LookChem

Useful:
  • Chemical Classes:Nitrogen Compounds -> Sulfonamides
  • Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)N
  • Recent ClinicalTrials:A Study of PTS100 in Primary HCC Patients
  • Inhalation Risk:A nuisance-causing concentration of airborne particles can be reached quickly when dispersed.
  • Effects of Short Term Exposure:May cause mechanical irritation to the eyes.
  • Uses 1. It is used in the manufacture of dyes, synthetic resins, paints, disinfectants and wood processing brightener. 2. It is used for the manufacture of plasticizers, disinfectants; it can also be used for the production of synthetic resins, paints, and fluorescent dyes. 3. It can be used as primary brightener in the bright nickel plating. It is sued for bright nickel plating for multilayer to obtain uniform bright coating. It has a commonly used amount of 0.2~0.3 g/L. 4. It can be used as plasticizers, also used for synthesis of organics, resins and saccharin. p-Toluenesulfonamide was used to prepare the precursor required for synthesis of ethyl 6-phenyl-1-tosyl-1,2,5,6-tetrahydropyridine-3-carboxylate. 4-Tolylsulfonamide is a carbonic anhydrase inhibitor used the synthesis of antiglaucoma and anticancer drugs. Used in the manufacture of plasticizer, disinfectant, fungicide, fungicides, wood brightener. Also can be used in the production of synthetic resin, the coating, the fluorescent dye, pharmaceutical, etc.
Technology Process of P-Toluenesulfonamide

There total 705 articles about P-Toluenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
chloroamine-T; benzyl alcohol; With saccharin; lithium bromide; In dichloromethane; at 20 ℃; for 3h;
In dichloromethane; Molecular sieve; Reflux;
DOI:10.1002/adsc.201000193
Guidance literature:
With 1-Benzyl-1,4-dihydronicotinamide; meso-tetraphenylporphyrin iron(III) chloride; In benzene; at 80 ℃; for 1h;
Guidance literature:
With 4-toluenesulfonyl azide; triethylamine; In tetrahydrofuran; at 50 ℃; for 20h;
DOI:10.1039/P19950001381
Refernces Edit
Post RFQ for Price