N-[2-(dimethylamino)ethyl]-2-phenylquinoline-8-carboxamide dihydrochloride

Base Information

Chemical Name:N-[2-(dimethylamino)ethyl]-2-phenylquinoline-8-carboxamide dihydrochloride
CAS No.:107026-86-8
Molecular Formula:C₂₀H₂₁N₃O*2ClH
Molecular Weight:392.328
Hs Code.:

Synonyms:8-Quinolinecarboxamide,N-[2-(dimethylamino)ethyl]-2-phenyl-, dihydrochloride (9CI)

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[2-(dimethylamino)ethyl]-2-phenylquinoline-8-carboxamide dihydrochloride

Chemical Property:

Vapor Pressure:2.67E-12mmHg at 25°C
Boiling Point:553.6°Cat760mmHg
Flash Point:288.6°C
Density:g/cm³

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N-[2-(dimethylamino)ethyl]-2-phenylquinoline-8-carboxamide dihydrochloride

There total 2 articles about N-[2-(dimethylamino)ethyl]-2-phenylquinoline-8-carboxamide dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5353-90-2
8-methyl-2-phenylquinoline

: 107026-86-8
N-<(2-dimethylamino)ethyl>-2-phenylquinoline-8-carboxamide dihydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: CrO₃

2: 1.) 1,1'-carbonyldiimidazole / 1.) DMF, 20-50 deg C, 30 min, 2.) 15 min

With chromium(VI) oxide; 1,1'-carbonyldiimidazole;
DOI:10.1021/jm00400a029

Reference yield:

: 5093-81-2
2-phenylquinoline-8-carboxylic acid

: 108-00-9
N,N-dimethylethylenediamine

: 107026-86-8
N-<(2-dimethylamino)ethyl>-2-phenylquinoline-8-carboxamide dihydrochloride

Guidance literature:: With 1,1'-carbonyldiimidazole; Yield given. Multistep reaction; 1.) DMF, 20-50 deg C, 30 min, 2.) 15 min;
DOI:10.1021/jm00400a029