4(5H)-Thiazolone, 2-amino-5-[(4-fluorophenyl)methylene]-

Base Information

Chemical Name:4(5H)-Thiazolone, 2-amino-5-[(4-fluorophenyl)methylene]-
CAS No.:78659-69-5
Molecular Formula:C10H7FN2OS
Molecular Weight:222.243
Hs Code.:
DSSTox Substance ID:DTXSID70385795

Synonyms:78659-69-5;4(5H)-Thiazolone, 2-amino-5-[(4-fluorophenyl)methylene]-;Enamine_000359;DTXSID70385795

Suppliers and Price of 4(5H)-Thiazolone, 2-amino-5-[(4-fluorophenyl)methylene]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4(5H)-Thiazolone, 2-amino-5-[(4-fluorophenyl)methylene]-

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:222.02631219
Heavy Atom Count:15
Complexity:332

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C=C2C(=O)N=C(S2)N)F

Technology Process of 4(5H)-Thiazolone, 2-amino-5-[(4-fluorophenyl)methylene]-

There total 1 articles about 4(5H)-Thiazolone, 2-amino-5-[(4-fluorophenyl)methylene]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 459-57-4
4-fluorobenzaldehyde

: 556-90-1
pseudothiohydantoin

: 78659-69-5
5-[1-(4-Fluoro-phenyl)-meth-(Z)-ylidene]-2-imino-thiazolidin-4-one

Guidance literature:: With sodium acetate; acetic acid; at 110 ℃; for 5h;
DOI:10.1016/j.ejmech.2019.111747

Reference yield: 96.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 78659-69-5
5-[1-(4-Fluoro-phenyl)-meth-(Z)-ylidene]-2-imino-thiazolidin-4-one

: 87446-94-4
5-[1-(4-Fluoro-phenyl)-meth-(Z)-ylidene]-2-(hydroxymethyl-amino)-thiazol-4-one

Guidance literature:: In 1,4-dioxane;
DOI:10.1007/BF00506099

Reference yield: 93.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 78659-69-5
5-[1-(4-Fluoro-phenyl)-meth-(Z)-ylidene]-2-imino-thiazolidin-4-one

: 62-53-3
aniline

: 88696-70-2
7-(4-fluorobenzylidene)-3,4-dihydro-3-phenyl-2H-thiazolo[3,2-a][1,3,5]triazin-6(7H)-one

Guidance literature:: formaldehyd; aniline; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

5-[1-(4-Fluoro-phenyl)-meth-(Z)-ylidene]-2-imino-thiazolidin-4-one; In N,N-dimethyl-formamide; at 100 ℃; for 6h;
DOI:10.1016/j.ejmech.2019.111747