2-(Azetidin-1-yl)ethan-1-amine

Base Information

Chemical Name:2-(Azetidin-1-yl)ethan-1-amine
CAS No.:795299-77-3
Molecular Formula:C₅H₁₂N₂
Molecular Weight:100.164
Hs Code.:2933998090
European Community (EC) Number:831-687-2
DSSTox Substance ID:DTXSID501314990
Nikkaji Number:J1.624.736G
Mol file:795299-77-3.mol

Synonyms:2-(azetidin-1-yl)ethan-1-amine;795299-77-3;1-Azetidineethanamine;2-(azetidin-1-yl)ethanamine;MFCD19205720;N-aminoethyl azetidine;N-(2-aminoethyl)azetidine;2-(1-Azetidinyl)ethanamine;2-(azetidin-1-yl)ethylamine;SCHEMBL1612176;RIHYLJLIMZMKTQ-UHFFFAOYSA-N;DTXSID501314990;AMY34670;AKOS006338332;SB50723;BS-12775;SY099362;CS-0127626;EN300-114312;P15319;Z1203582961

Suppliers and Price of 2-(Azetidin-1-yl)ethan-1-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
1-Azetidineethanamine
250mg
$ 523.00

TRC
1-Azetidineethanamine
1g
$ 550.00

TRC
1-Azetidineethanamine
500mg
$ 330.00

Chemenu
2-(azetidin-1-yl)ethan-1-amine 95+%
10g
$ 577.00

American Custom Chemicals Corporation
2-(AZETIDIN-1-YL)ETHAN-1-AMINE 95.00%
5MG
$ 451.08

AK Scientific
2-(Azetidin-1-yl)ethan-1-amine
250mg
$ 653.00

Total 13 raw suppliers

Chemical Property of 2-(Azetidin-1-yl)ethan-1-amine

Chemical Property:

Boiling Point:155.1±8.0 °C(Predicted)
PKA:9.62±0.10(Predicted)
PSA：29.26000
Density:0.969±0.06 g/cm3(Predicted)
LogP:0.28900
XLogP3:-0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:100.100048391
Heavy Atom Count:7
Complexity:50

Purity/Quality:

99%, ^*data from raw suppliers

1-Azetidineethanamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CN(C1)CCN
Uses 1-Azetidineethanamine is a reagent used in the synthesis of analogs of geldanamycin with superior inhibition ability towards the growth of human cancer cells.

Technology Process of 2-(Azetidin-1-yl)ethan-1-amine

There total 2 articles about 2-(Azetidin-1-yl)ethan-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: {2-[(tert-butoxycarbonyl)amino]ethyl}azetidine

: 795299-77-3
2-(azetidin-1-yl)ethan-1-amine

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; dichloromethane; at 20 ℃; for 16h;

Reference yield: 48.0%

: 503-29-7
azetidine

: 107-14-2
chloroacetonitrile

: 795299-77-3
2-(azetidin-1-yl)ethan-1-amine

Guidance literature:: azetidine; chloroacetonitrile; With potassium carbonate; nickel; In diethyl ether; acetonitrile; at 20 ℃; for 20.1667h;

With ammonia; hydrogen; In methanol; at 60 ℃; for 2h; under 15001.5 Torr;

Reference yield:

: 795299-77-3
2-(azetidin-1-yl)ethan-1-amine

: 3-((2-(azetidin-1-yl)ethylamino)methyl)-4-methoxybenzenamine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tris(acetoxy)borohydride / 1,2-dichloro-ethane / 2 h / 25 °C

2: Raney nickel / methanol / 2 h / 25 °C / Inert atmosphere

With sodium tris(acetoxy)borohydride; In methanol; 1,2-dichloro-ethane;