3-(3-Fluorobenzoyl)pyridine

Base Information

Chemical Name:3-(3-Fluorobenzoyl)pyridine
CAS No.:79568-07-3
Molecular Formula:C12H8FNO
Molecular Weight:201.2
Hs Code.:
DSSTox Substance ID:DTXSID70513238
Nikkaji Number:J1.628.371A
Wikidata:Q82372931

Synonyms:3-(3-Fluorobenzoyl)pyridine;79568-07-3;(3-Fluorophenyl)(pyridin-3-yl)methanone;Methanone, (3-fluorophenyl)-3-pyridinyl-;MFCD12153285;(3-fluorophenyl)-pyridin-3-ylmethanone;3-(3-Fluorobenzoyl)-pyridine;SCHEMBL10487079;DTXSID70513238;IEVCOTJIGFKWIC-UHFFFAOYSA-N;AKOS010014462;(3-fluorophenyl)-(3-pyridyl)methanone;A1-24743

Suppliers and Price of 3-(3-Fluorobenzoyl)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 3-(3-Fluorobenzoyl)pyridine

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:201.058992041
Heavy Atom Count:15
Complexity:232

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)F)C(=O)C2=CN=CC=C2

Technology Process of 3-(3-Fluorobenzoyl)pyridine

There total 5 articles about 3-(3-Fluorobenzoyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 100-54-9,121697-66-3,1232169-17-3,68271-95-4
pyridine-3-carbonitrile

: 1073-06-9
3-fluorobromobenzene

: 79568-07-3
(3-fluorophenyl)(pyridin-3-yl)methanone

Guidance literature:: With tert.-butyl lithium; Yield given. Multistep reaction; 1.) ether, pentane, -78 deg C, 15 min;
DOI:10.1021/jm00164a051

Reference yield:

: 79568-05-1
3-nitrophenyl 3-pyridyl ketone

: 79568-07-3
(3-fluorophenyl)(pyridin-3-yl)methanone

Guidance literature:: Multi-step reaction with 3 steps

1: 66 percent / SnCl₂, HCl

2: NaNO₂, HBF₄ / tetrahydrofuran; H₂O / 0.5 h / -10 °C

3: 0.25 h / Heating

With hydrogenchloride; tetrafluoroboric acid; tin(ll) chloride; sodium nitrite; In tetrahydrofuran; water;
DOI:10.1021/jm00144a025

Reference yield:

: 79568-06-2
3-(3-aminobenzoyl)pyridine

: 79568-07-3
(3-fluorophenyl)(pyridin-3-yl)methanone

Guidance literature:: Multi-step reaction with 2 steps

1: NaNO₂, HBF₄ / tetrahydrofuran; H₂O / 0.5 h / -10 °C

2: 0.25 h / Heating

With tetrafluoroboric acid; sodium nitrite; In tetrahydrofuran; water;
DOI:10.1021/jm00144a025