Aziridine, 1-[(4-methylphenyl)sulfonyl]-2-(2-pyridinyl)-

Base Information

Chemical Name:Aziridine, 1-[(4-methylphenyl)sulfonyl]-2-(2-pyridinyl)-
CAS No.:796975-18-3
Molecular Formula:C14H14N2O2S
Molecular Weight:274.343
Hs Code.:
DSSTox Substance ID:DTXSID40460609
Nikkaji Number:J2.101.533D

Synonyms:796975-18-3;2-(1-Tosylaziridin-2-yl)pyridine;2-[1-(4-METHYLBENZENESULFONYL)AZIRIDIN-2-YL]PYRIDINE;Aziridine, 1-[(4-methylphenyl)sulfonyl]-2-(2-pyridinyl)-;N-Tosyl-2-(o-pyridyl)aziridine;DTXSID40460609

Suppliers and Price of Aziridine, 1-[(4-methylphenyl)sulfonyl]-2-(2-pyridinyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Aziridine, 1-[(4-methylphenyl)sulfonyl]-2-(2-pyridinyl)-

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:274.07759887
Heavy Atom Count:19
Complexity:410

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)N2CC2C3=CC=CC=N3

Technology Process of Aziridine, 1-[(4-methylphenyl)sulfonyl]-2-(2-pyridinyl)-

There total 4 articles about Aziridine, 1-[(4-methylphenyl)sulfonyl]-2-(2-pyridinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 100-69-6,25014-15-7,27476-03-5,329041-71-6
2-vinylpyridine

: 70-55-3
toluene-4-sulfonamide

: 796975-18-3
2-(N-tosylaziridin-2-yl)pyridine

Guidance literature:: With tetrakis(actonitrile)copper(I) hexafluorophosphate; iodosylbenzene; In acetonitrile; at 0 - 23 ℃; Molecular sieve; Inert atmosphere;
DOI:10.1002/chem.201303699

Reference yield: 27.0%

: 100-69-6,25014-15-7,27476-03-5,329041-71-6
2-vinylpyridine

: 4-methyl-N-(pivaloyloxy)benzenesulfonamide

: 796975-18-3
2-(N-tosylaziridin-2-yl)pyridine

Guidance literature:: With iron(II) triflate; 2,6-bis[4’,4’-dimethyloxazolin-2’-yl]pyridine; In acetonitrile; at 70 ℃; for 18h; Inert atmosphere;
DOI:10.1039/d1gc03495b

Reference yield:

: 1593-60-8
p-toluenesulfonylhydroxylamine

: 796975-18-3
2-(N-tosylaziridin-2-yl)pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 2 h / 0 °C / Inert atmosphere

2: 2,6-bis[4’,4’-dimethyloxazolin-2’-yl]pyridine; iron(II) triflate / acetonitrile / 18 h / 70 °C / Inert atmosphere

With iron(II) triflate; triethylamine; 2,6-bis[4’,4’-dimethyloxazolin-2’-yl]pyridine; In dichloromethane; acetonitrile;
DOI:10.1039/d1gc03495b