Bicyclo[3.3.1]nonane-2,6-dione, (1R)-

Base Information

• Chemical Name: Bicyclo[3.3.1]nonane-2,6-dione, (1R)-
• CAS No.: 79767-50-3
• Molecular Formula: C9H12O2
• Molecular Weight: 152.19000
• Mol file: 79767-50-3.mol

Synonyms:bicyclo[3.3.1]nonane-2,6-dione;(1R,5R)-bicyclo[3.3.1]nonane-2,6-dione;Bicyclo[3.3.1]nonan-2,6-dion;

Chemical Property of Bicyclo[3.3.1]nonane-2,6-dione, (1R)-

Chemical Property:

• PSA: 34.14000
• LogP: 1.33470

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Bicyclo[3.3.1]nonane-2,6-dione, (1R)-

There total 10 articles about Bicyclo[3.3.1]nonane-2,6-dione, (1R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

6-hydroxybicyclo[3.3.1]nonan-2-one (1092543-24-2) → (-)-(1R,5R)-bicyclo[3.3.1]nonane-2,6-dione (79767-50-3)

Guidance literature:

With tetrapropylammonium perruthennate; 4 A molecular sieve; 4-methylmorpholine N-oxide; In dichloromethane; at 20 ℃; for 0.333333h;

DOI:10.1055/s-0028-1083364

Reference yield:

dimethyl rac-(1R,2S,4R,5S)-bicyclo[2.2.1]heptane-2,5-dicarboxylate → Bicyclo<3.3.1>nonan-2,6-diol (16473-12-4) + (S,S)-bicyclo[3.3.1]nonane-2,6-dione (36415-87-9) + 6-Hydroxy-bicyclo[3.3.1]nonan-2-one (67388-67-4) + (-)-(1R,5R)-bicyclo[3.3.1]nonane-2,6-dione (79767-50-3)

Guidance literature:

With baker's yeast; Sucrose; In water; for 6h;

DOI:10.1016/S0957-4166(02)00157-X

Reference yield:

bicyclo[3.3.1]nonane-2,6-dione (16473-11-3) → Bicyclo<3.3.1>nonan-2,6-diol (16473-12-4) + (S,S)-bicyclo[3.3.1]nonane-2,6-dione (36415-87-9) + (-)-(1R,5R)-bicyclo[3.3.1]nonane-2,6-dione (79767-50-3) + (1S,5S,6R)-6-Hydroxy-bicyclo[3.3.1]nonan-2-one

Guidance literature:

With horse liver alcohol dehydrogenase; NAD; In phosphate buffer; ethanol; at 30 ℃; for 24h; pH=7.5; Product distribution; Enzymatic reaction;

DOI:10.1021/jo991385a

upstream raw materials:

(-)-(1R,2S,5R,6S)-bicyclo<3.3.1>nonane-2,6-diol

bicyclo[3.3.1]nonane-2,6-dione

bicyclo[3.3.1]nonane-2,6-dione

6-hydroxybicyclo[3.3.1]nonan-2-one