6,6-Ethylene-15,16-methylene-3-oxo-17-pregn-4-ene-2,17-carbolactone

Base Information

Chemical Name:6,6-Ethylene-15,16-methylene-3-oxo-17-pregn-4-ene-2,17-carbolactone
CAS No.:101765-35-9
Molecular Formula:C₂₅H₃₂O₃
Molecular Weight:380.527
Hs Code.:
DSSTox Substance ID:DTXSID20144177
Nikkaji Number:J421.153G
Wikidata:Q83008283
Mol file:101765-35-9.mol

Synonyms:6,6-EMOPC;6,6-ethylene-15,16-methylene-3-oxo-17-pregn-4-ene-2,17-carbolactone

Suppliers and Price of 6,6-Ethylene-15,16-methylene-3-oxo-17-pregn-4-ene-2,17-carbolactone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 6,6-Ethylene-15,16-methylene-3-oxo-17-pregn-4-ene-2,17-carbolactone

Chemical Property:

Vapor Pressure:6.35E-13mmHg at 25°C
Boiling Point:568.1°Cat760mmHg
Flash Point:247.3°C
PSA：43.37000
Density:1.24g/cm³
LogP:4.84010
XLogP3:4.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:380.23514488
Heavy Atom Count:28
Complexity:852

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC12CCC(=O)C=C1C3(CC3)CC4C2CCC5(C4C6CC6C57CCC(=O)O7)C
Isomeric SMILES:C[C@]12CCC(=O)C=C1C3(CC3)C[C@@H]4[C@@H]2CC[C@]5([C@H]4[C@@H]6C[C@@H]6[C@@]57CCC(=O)O7)C

Technology Process of 6,6-Ethylene-15,16-methylene-3-oxo-17-pregn-4-ene-2,17-carbolactone

There total 3 articles about 6,6-Ethylene-15,16-methylene-3-oxo-17-pregn-4-ene-2,17-carbolactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67372-68-3
3-oxo-15β,16β-methylene-17α-pregn-4-en-21,17-carbolactone

: 101765-35-9
6,6-ethylene-15β,16β-methylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) pyrrolidine / 1.) methanol, reflux, 15 min, 2.) ethanol, benzene, H₂O, 30 min

2: aq. HCl / dioxane / 2 h

3: 1.) NaH / 1.) DMSO, RT, 1.5 h, 2.) DMSO, RT, 50 min

With pyrrolidine; hydrogenchloride; sodium hydride; In 1,4-dioxane;
DOI:10.1021/jm00112a022

Reference yield:

: 101765-34-8,101765-38-2
C₂₄H₃₂O₄

: 101765-35-9
6,6-ethylene-15β,16β-methylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone

Guidance literature:: Multi-step reaction with 2 steps

1: aq. HCl / dioxane / 2 h

2: 1.) NaH / 1.) DMSO, RT, 1.5 h, 2.) DMSO, RT, 50 min

With hydrogenchloride; sodium hydride; In 1,4-dioxane;
DOI:10.1021/jm00112a022

Reference yield:

: 1030268-24-6
trimethylsulphoxonium iodide

: 84529-99-7
6:15β,16β-dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone

: 101765-35-9
6,6-ethylene-15β,16β-methylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone

Guidance literature:: With sodium hydride; Yield given. Multistep reaction; 1.) DMSO, RT, 1.5 h, 2.) DMSO, RT, 50 min;
DOI:10.1021/jm00112a022