2-Pyrrolidinone,4-hydroxy-, (4R)-

Base Information

Chemical Name:2-Pyrrolidinone,4-hydroxy-, (4R)-
CAS No.:22677-21-0
Molecular Formula:C4H7NO2
Molecular Weight:101.105
Hs Code.:DERIVATION
Mol file:22677-21-0.mol

Synonyms:2-Pyrrolidinone,4-hydroxy-, (R)- (8CI);(4R)-4-Hydroxy-2-pyrrolidinone;(4R)-4-Hydroxypyrrolidin-2-one;(R)-4-Hydroxy-2-pyrrolidinone;(R)-4-Hydroxypyrrolidin-2-one;

Suppliers and Price of 2-Pyrrolidinone,4-hydroxy-, (4R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Abosyn
(R)-4-Hydroxypyrrolidin-2-one 95%-98%
1g
$ 81.00

Abosyn
(R)-4-Hydroxypyrrolidin-2-one 95%-98%
10g
$ 441.00

ACHEMBLOCK
(4R)-4-Hydroxy-2-pyrrolidinone 97%
500MG
$ 85.00

ACHEMBLOCK
(4R)-4-Hydroxy-2-pyrrolidinone 97%
1G
$ 140.00

Acrotein
(4R)-4-Hydroxy-2-pyrrolidinone 97%
5g
$ 333.67

Activate Scientific
(R)-4-Hydroxy-2-pyrrolidone 95+% ee
5 g
$ 214.00

Activate Scientific
(R)-4-Hydroxy-2-pyrrolidone 95+% ee
1 g
$ 71.00

AHH
(R)-4-Hydroxy-2-pyrrolidone 98%
50g
$ 788.00

AK Scientific
(R)-4-Hydroxypyrrolidin-2-one
1g
$ 174.00

Alfa Aesar
(R)-(+)-4-Hydroxy-2-pyrrolidinone, 97+%
250mg
$ 37.10

Total 85 raw suppliers

Chemical Property of 2-Pyrrolidinone,4-hydroxy-, (4R)-

Chemical Property:

Appearance/Colour:white to light yellow crystal powder
Vapor Pressure:9.26E-07mmHg at 25°C
Melting Point:156-160 °C
Refractive Index:1.513
Boiling Point:363.6 °C at 760 mmHg
PKA:13.62±0.20(Predicted)
Flash Point:173.7 °C
PSA：49.33000
Density:1.292 g/cm³
LogP:-0.80400
Storage Temp.:Sealed in dry,Room Temperature
Solubility.:DMSO (Sparingly), Methanol (Slightly), Water (Sparingly)
Water Solubility.:Slightly soluble in water.

Purity/Quality:

99% ^*data from raw suppliers

(R)-4-Hydroxypyrrolidin-2-one 95%-98% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes: Xi:Irritant;
Statements: R36/37/38:;
Safety Statements: S26:;

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Uses The (R)-enantiomer intermediate in the preparation of Oxiracetam (R)-(+)-4-Hydroxy-2-pyrrolidinone intermediate in the preparation of Oxiracetam. Also used as enantiomeric intermediate for the asymmetric single isomeric drugs including antitumor, anesthetic, antipasmodic, anti-inflammatory or anti-HIV activity products.

Technology Process of 2-Pyrrolidinone,4-hydroxy-, (4R)-

There total 19 articles about 2-Pyrrolidinone,4-hydroxy-, (4R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%