Ethyl s-4-chloro-3-hydroxybutyrate

Base Information

Chemical Name:Ethyl s-4-chloro-3-hydroxybutyrate
CAS No.:86728-85-0
Molecular Formula:C₆H₁₁ClO₃
Molecular Weight:166.605
Hs Code.:29181990
UNII:4LVQ2A7DDJ
DSSTox Substance ID:DTXSID00427096
Nikkaji Number:J455.989D
Wikidata:Q72473625
Mol file:86728-85-0.mol

Synonyms:86728-85-0;ethyl s-4-chloro-3-hydroxybutyrate;Ethyl (S)-(-)-4-chloro-3-hydroxybutyrate;Ethyl (S)-4-Chloro-3-hydroxybutyrate;ethyl (S)-4-chloro-3-hydroxybutanoate;ethyl (3S)-4-chloro-3-hydroxybutanoate;ethyl (S)-(-)-4-chloro-3-hydroxybutanoate;MFCD00211241;(S)-4-Chloro-3-hydroxy-n-butyric Acid Ethyl Ester;(S)-Ethyl 4-chloro-3-hydroxybutanoate;(S)-4-Chloro-3-hydroxybutyric Acid Ethyl Ester;S-4-Chloro-3-hydroxybutyrate;ethyl(S)-4-chloro-3-hydroxybutyrate;Ethyl(S)-(-)-4-chloro-3-hydroxybutyrate;4LVQ2A7DDJ;SCHEMBL96394;(-)-ETHYL (S)-4-CHLORO-3-HYDROXYBUTYRATE;DTXSID00427096;ZAJNMXDBJKCCAT-YFKPBYRVSA-N;ethyl (S)-4-chloro3-hydroxybutyrate;(S)-ethyl-4-chloro-3-hydroxybutyrate;AKOS006239591;AKOS015838752;ethyl (S) 4-chloro-3-hydroxybutyrate;ethyl 4-chloro-(S)-3-hydroxybutyrate;ethyl(3S)-4-chloro-3-hydroxybutyrate;(S)-Ethyl 4-chloro-3-hydroxybutyrate;AM81438;CS-W017853;ethyl (3S)-4-chloro-3-hydroxybutyrate;AS-14912;Ethyl (S)-4-Chloro-3-Hydroxy Butanoate;ethyl (3S)-4-chloro-3-hydroxy-butanoate;C1717;EN300-108384;(3s)-4-chloro-3-hydroxybutyric acid ethyl ester;(s)-4-chloro-3- hydroxybutanoic acid ethyl ester;Ethyl (S)-(-)-4-chloro-3-hydroxybutyrate, 96%;4-Chloro-3-hydroxybutyric acid ethyl ester, (3S)-;J-524234;Butanoic acid, 4-chloro-3-hydroxy-, ethyl ester, (3S)-;Ethyl S-4-chloro-3-hydroxybutyrate;Ethyl (S)-(-)-4-Chloro-3-hydroxybutyrate

Suppliers and Price of Ethyl s-4-chloro-3-hydroxybutyrate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ACHEMBLOCK
(S)-Ethyl4-chloro-3-hydroxybutanoate 95%
25G
$ 225.00

ACHEMBLOCK
(S)-Ethyl4-chloro-3-hydroxybutanoate 95%
100G
$ 610.00

Acrotein
(S)-Ethyl4-chloro-3-hydroxybutanoate 97%
5g
$ 55.00

AHH
Ethyl(S)-(-)-4-chloro-3-hydroxybutanoate 98%
50g
$ 358.00

AK Scientific
Ethyl (S)-(?)-4-chloro-3-hydroxybutyrate
1g
$ 15.00

Alfa Aesar
Ethyl (S)-(-)-4-chloro-3-hydroxybutyrate, 98%, ee 98%
1g
$ 24.40

Alfa Aesar
Ethyl (S)-(-)-4-chloro-3-hydroxybutyrate, 98%, ee 98%
5g
$ 99.10

Ambeed
Ethyl(S)-4-chloro-3-hydroxybutanoate 97%
25g
$ 19.00

Ambeed
Ethyl(S)-4-chloro-3-hydroxybutanoate 97%
1kg
$ 355.00

American Custom Chemicals Corporation
(S)-(-)-4-CHLORO-3-HYDROXYBUTYRATE 95.00%
5MG
$ 501.22

Total 200 raw suppliers

Chemical Property of Ethyl s-4-chloro-3-hydroxybutyrate

Chemical Property:

Appearance/Colour:colorless to light yellow liquid
Vapor Pressure:0.00145mmHg at 25°C
Refractive Index:n20/D 1.453(lit.)
Boiling Point:263.4 °C at 760 mmHg
PKA:13.23±0.20(Predicted)
Flash Point:113.1 °C
PSA：46.53000
Density:1.187 g/cm³
LogP:0.53930
Storage Temp.:Refrigerator
XLogP3:0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:166.0396719
Heavy Atom Count:10
Complexity:105

Purity/Quality:

≥98.0% ^*data from raw suppliers

(S)-Ethyl4-chloro-3-hydroxybutanoate 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,Xn
Statements: 41-22
Safety Statements: 26-36-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CC(CCl)O
Isomeric SMILES:CCOC(=O)C[C@@H](CCl)O
Uses Ethyl (S)-(?)-4-chloro-3-hydroxybutyrate can be used as a starting material in the synthesis of 4-amino-3-hydroxybutyric acid, a compound of pharmacological importance.

Technology Process of Ethyl s-4-chloro-3-hydroxybutyrate

There total 36 articles about Ethyl s-4-chloro-3-hydroxybutyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 638-07-3
ethyl (2-chloroaceto)acetate

: 10488-69-4,86728-85-0,87068-18-6,90866-33-4
ethyl (S)-4-chloro-3-hydroxybutanoate

Guidance literature:: With formic acid; NAD; sodium formate; formate dehydrogenase; In water; at 30 ℃; for 3.5h; pH=6.5;
DOI:10.1271/bbb.69.544

Reference yield: 99.0%

: 638-07-3
ethyl (2-chloroaceto)acetate

: 10488-69-4,86728-85-0,87068-18-6,90866-33-4
ethyl (L)-4-chloro-3-hydroxybutyrate

Guidance literature:: With D-glucose; β-keto ester reductase L-1; tris hydrochloride; NADPH; at 30 ℃; for 48h; relative reaction rate; other β-keto esters; var. time;
DOI:10.1246/bcsj.67.524