N-Benzoyl-2'-O-[(4-methoxyphenyl)methyl]cytidine

Base Information

Chemical Name:N-Benzoyl-2'-O-[(4-methoxyphenyl)methyl]cytidine
CAS No.:80015-59-4
Molecular Formula:C24H25N3O7
Molecular Weight:467.478
Hs Code.:
DSSTox Substance ID:DTXSID60559281
Wikidata:Q82441948

Synonyms:80015-59-4;N-Benzoyl-2'-O-[(4-methoxyphenyl)methyl]cytidine;DTXSID60559281

Suppliers and Price of N-Benzoyl-2'-O-[(4-methoxyphenyl)methyl]cytidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N-Benzoyl-2'-O-[(4-methoxyphenyl)methyl]cytidine

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:8
Exact Mass:467.16925015
Heavy Atom Count:34
Complexity:775

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)COC2C(C(OC2N3C=CC(=NC3=O)NC(=O)C4=CC=CC=C4)CO)O
Isomeric SMILES:COC1=CC=C(C=C1)CO[C@@H]2[C@@H]([C@H](O[C@H]2N3C=CC(=NC3=O)NC(=O)C4=CC=CC=C4)CO)O

Technology Process of N-Benzoyl-2'-O-[(4-methoxyphenyl)methyl]cytidine

There total 5 articles about N-Benzoyl-2'-O-[(4-methoxyphenyl)methyl]cytidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 98-88-4
benzoyl chloride

: 80015-55-0
2'-O-(4-methoxybenzyl)cytidine

: 80015-59-4
2'-O-(4-methoxybenzyl)-N⁴-benzoylcytidine

Guidance literature:: With pyridine; for 3h; Ambient temperature;
DOI:10.1021/jo00175a010

Reference yield: 30.0%

: 23304-25-8
p-methoxyphenyldiazomethane

: 13089-48-0
N₄-benzoylcytidine

: 80015-59-4
2'-O-(4-methoxybenzyl)-N⁴-benzoylcytidine

: 85193-76-6
3'-O-(4-methoxybenzyl)-N⁴-benzoylcytidine

Guidance literature:: With tin(ll) chloride; In dichloromethane; N,N-dimethyl-formamide; at 45 ℃; for 2h;
DOI:10.1016/S0040-4020(01)82051-2

Reference yield:

: 65-46-3
CYTIDINE

: 80015-59-4
2'-O-(4-methoxybenzyl)-N⁴-benzoylcytidine

Guidance literature:: Multi-step reaction with 2 steps

1: dimethylformamide / 1 h / -5 °C

2: 87 percent / pyridine / 3 h / Ambient temperature

With pyridine; In N,N-dimethyl-formamide;
DOI:10.1021/jo00175a010