1,2-Dicarbadodecaborane(12), 1-heptyl-

Base Information

• Chemical Name: 1,2-Dicarbadodecaborane(12), 1-heptyl-
• CAS No.: 126223-53-8
• Molecular Formula: C₉H₂₆B₁₀
• Molecular Weight: 242.415
• Mol file: 126223-53-8.mol

Synonyms:1-Heptyl-o-carborane(12)

Chemical Property of 1,2-Dicarbadodecaborane(12), 1-heptyl-

Chemical Property:

• Boiling Point: 131 - 132 °C (1 mmHg)
• PSA: 0.00000
• LogP: -3.34570

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,2-Dicarbadodecaborane(12), 1-heptyl-

There total 5 articles about 1,2-Dicarbadodecaborane(12), 1-heptyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

B10H10CC7H15CSi(CH3)2C(CH3)3 (1227007-91-1) → 1-(n-heptyl)-1,2-dicarba-closo-dodecaborane (126223-53-8)

Guidance literature:

With tetrabutylammonium fluoride; In tetrahydrofuran; (Ar) (C4H9)NF in THF was added to a soln. of carborane-compound in THF at -78°C over 10 min, the mixt. was warmed to room temp., stirred for 30 min; water was added, extd. with diethyl ether, the solvent was removed, silica gel column chromy. using hexane as eluent; as oil;

DOI:10.1021/ja101845m

Reference yield: 93.0%

1-(bromoethyl)-1,2-dicarba-closo-dodecaborane (24035-02-7) + n-pentylmagnesium bromide (693-25-4) → 1-(n-heptyl)-1,2-dicarba-closo-dodecaborane (126223-53-8)

Guidance literature:

With triphenylphosphine; copper dichloride; In tetrahydrofuran; at 25 ℃; for 6h; Inert atmosphere;

DOI:10.1016/j.tet.2015.11.019

Reference yield: 90.0%

1-(bromoethyl)-1,2-dicarba-closo-dodecaborane (24035-02-7) + pentylmagnesium chloride (6393-56-2) → 1-(n-heptyl)-1,2-dicarba-closo-dodecaborane (126223-53-8)

Guidance literature:

With triphenylphosphine; copper dichloride; In tetrahydrofuran; at 25 ℃; for 12h; Inert atmosphere;

DOI:10.1016/j.tet.2015.11.019

upstream raw materials:

1-nonyne

B₁₀H₁₀CC₇H₁₅CSi(CH₃)2C(CH₃)3

1-(bromoethyl)-1,2-dicarba-closo-dodecaborane

n-pentylmagnesium bromide

Downstream raw materials:

B₁₀H₁₀CC₇H₁₅CCH₂C₆H₄I

Refernces

• 1、 Lu, Ju-You,Du, Yongmei,Zhao, Bo,Lu, Jian. "Copper-catalyzed cross-coupling of 1-haloalkyl-o-carboranes with Grignard reagents: An efficient route to monosubstituted o-carborane derivatives". supporting information. p. 161 - 169. Retrieved 2015/12/23.