1-[4-(Benzyloxy)phenyl]-3-(1H-pyrazol-1-yl)propan-1-one

Base Information

Chemical Name:1-[4-(Benzyloxy)phenyl]-3-(1H-pyrazol-1-yl)propan-1-one
CAS No.:80199-83-3
Molecular Formula:C19H18N2O2
Molecular Weight:306.364
Hs Code.:
DSSTox Substance ID:DTXSID30603528
Wikidata:Q82500965

Synonyms:80199-83-3;SCHEMBL10790521;DTXSID30603528;1-[4-(Benzyloxy)phenyl]-3-(1H-pyrazol-1-yl)propan-1-one

Suppliers and Price of 1-[4-(Benzyloxy)phenyl]-3-(1H-pyrazol-1-yl)propan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-[4-(Benzyloxy)phenyl]-3-(1H-pyrazol-1-yl)propan-1-one

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:7
Exact Mass:306.136827821
Heavy Atom Count:23
Complexity:360

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC2=CC=C(C=C2)C(=O)CCN3C=CC=N3

Technology Process of 1-[4-(Benzyloxy)phenyl]-3-(1H-pyrazol-1-yl)propan-1-one

There total 1 articles about 1-[4-(Benzyloxy)phenyl]-3-(1H-pyrazol-1-yl)propan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 288-13-1
NH-pyrazole

: 51345-76-7
1-(dimethylamino)-3-<4-(benzyloxy)phenyl>propan-3-one

: 80199-83-3
4'-(benzyloxy)-3-(1-pyrazolyl)propiophenone

Guidance literature:: In butan-1-ol; for 15h; Heating;
DOI:10.1021/jm00370a012

Reference yield: 98.0%

: 80199-83-3
4'-(benzyloxy)-3-(1-pyrazolyl)propiophenone

: 80199-84-4
4-(benzyloxy)-α-<2-(1-pyrazolyl)ethyl>benzyl alcohol

Guidance literature:: With sodium tetrahydroborate; In ethanol; for 2h;
DOI:10.1021/jm00370a012

Reference yield:

: 80199-83-3
4'-(benzyloxy)-3-(1-pyrazolyl)propiophenone

: 88670-70-6
4-<3-(1-pyrazolyl)propyl>phenol hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / sodium borohydride / ethanol / 2 h

2: concd HCl, H₂ / 10percent Pd/C / ethanol / 760 Torr / Ambient temperature

With hydrogenchloride; sodium tetrahydroborate; hydrogen; palladium on activated charcoal; In ethanol;
DOI:10.1021/jm00370a012