Tris(4-methoxyphenyl)phosphine oxide

Base Information

• Chemical Name: Tris(4-methoxyphenyl)phosphine oxide
• CAS No.: 803-17-8
• Molecular Formula: C21H21O4P
• Molecular Weight: 368.369
• DSSTox Substance ID: DTXSID40388894
• Nikkaji Number: J402.387K
• Mol file: 803-17-8.mol

Synonyms:tris(4-methoxyphenyl)phosphine oxide;803-17-8;Tris-p-anisylphosphine oxide;Tris(p-anisyl)phosphine oxide;SCHEMBL1001220;DTXSID40388894;KSTMQPBYFFFVFI-UHFFFAOYSA-N;tri(p-methoxyphenyl) phosphine oxide

Chemical Property of Tris(4-methoxyphenyl)phosphine oxide

Chemical Property:

• Vapor Pressure: 1.46E-11mmHg at 25°C
• XLogP3: 4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 368.11774614
• Heavy Atom Count: 26
• Complexity: 392

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)P(=O)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC

Technology Process of Tris(4-methoxyphenyl)phosphine oxide

There total 19 articles about Tris(4-methoxyphenyl)phosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

P(p-CH3OC6H4)3 (855-38-9) → Tris(4-methoxyphenyl)phosphine oxide (803-17-8)

Guidance literature:

With 4-phenylthioxanthone; In methanol; at 20 ℃; for 0.666667h; under 760.051 Torr; Solvent; Mechanism; Irradiation;

DOI:10.1016/j.tetlet.2018.09.031

Reference yield: 93.0%

tris-p-methoxyphenylphosphine sulphide (14180-55-3) → Tris(4-methoxyphenyl)phosphine oxide (803-17-8)

Guidance literature:

With 2-methyl-3-p-nitrophenyloxaziridine; In chloroform-d1; at 40 ℃; for 72h; Irradiation;

Reference yield: 60.0%

tris-p-methoxyphenylphosphine sulphide (14180-55-3) + 2-methyl-3-p-nitrophenyloxaziridine (3400-27-9,28944-73-2,28958-67-0,59862-71-4,59862-72-5) → (E)-N-methyl-1-(4-nitrophenyl)methanimine (59862-73-6) + Tris(4-methoxyphenyl)phosphine oxide (803-17-8) + 4-nitrobenzaldehdye (555-16-8)

Guidance literature:

In chloroform-d1; at 40 ℃; for 72h; Rate constant; Product distribution; Irradiation;

upstream raw materials:

P(p-CH₃OC₆H₄)3

Tris-(4-methoxy-phenyl)-ethoxy-carbonylmethylenphosphoran

3,3,4,4-tetramethyl-1,2-dioxetane

tris-p-methoxyphenylphosphine sulphide

Downstream raw materials:

Tris(4-hydroxyphenyl)phosphine oxide

[Rh(CO)(OP(CH₃OC₆H₄)3)(P(C₆H₅)3)2]⁽¹⁺⁾*ClO₄^(1-)=[Rh(CO)(OP(CH₃OC₆H₄)3)(P(C₆H₅)3)2]ClO₄

bis(4-methoxyphenyl)phosphine oxide

Refernces

• 1、 Landais, Yannick,Laye, Claire,Lusseau, Jonathan,Robert, Frédéric. "The Trityl-Cation Mediated Phosphine Oxides Reduction". supporting information. p. 3035 - 3043. Retrieved 2021/05/10.
• 2、 Kishida, Natsuki,Suzuki, Hayate,Toyota, Shinji,Yamashina, Masahiro,Yoshizawa, Michito. "Synthesis of Azaylide-Based Amphiphiles by the Staudinger Reaction". supporting information. p. 17915 - 17919. Retrieved 2021/07/09.