Prchvhrsrvemey-uhfffaoysa-N

Base Information

• Chemical Name: Prchvhrsrvemey-uhfffaoysa-N
• CAS No.: 80322-82-3
• Molecular Formula: C8H18O8S2
• Molecular Weight: 306.358
• DSSTox Substance ID: DTXSID10703833
• Mol file: 80322-82-3.mol

Synonyms:SCHEMBL1627441;DTXSID10703833;PRCHVHRSRVEMEY-UHFFFAOYSA-N;AKOS030254744;FT-0675470;Methanesulfonic acid--2,2'-[ethane-1,2-diylbis(oxy)]di(ethan-1-ol) (2/1)

Chemical Property of Prchvhrsrvemey-uhfffaoysa-N

Chemical Property:

• PSA: 121.96000
• LogP: 1.13360
• Storage Temp.: Refrigerator, under inert atmosphere
• Solubility.: Chlroform (Sparingly), Methanol (Slightly)
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 7
• Exact Mass: 342.06543924
• Heavy Atom Count: 20
• Complexity: 142

Purity/Quality:

98%,99%, ^*data from raw suppliers

TriethyleneGlycolDimethanesulfonate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CS(=O)(=O)O.CS(=O)(=O)O.C(COCCOCCO)O

Technology Process of Prchvhrsrvemey-uhfffaoysa-N

There total 2 articles about Prchvhrsrvemey-uhfffaoysa-N which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

methanesulfonyl chloride (124-63-0) + 2,2'-[1,2-ethanediylbis(oxy)]bisethanol (112-27-6) → triethyleneglycol dimesylate (80322-82-3)

Guidance literature:

With triethylamine; In dichloromethane;

DOI:10.1016/S0040-4039(01)00619-0

Reference yield: 96.07%

→ triethyleneglycol dimesylate (80322-82-3)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 4h;

Reference yield: 89.0%

triethyleneglycol dimesylate (80322-82-3) + 1-O-benzyl-2-hydroxy-dodecane (109538-39-8) → 1-benzyloxy-2-(2-{2-[2-(1-benzyloxyethyl-undecyloxy)-ethoxy]-ethoxy}-ethoxy)dodecane (235091-02-8)

Guidance literature:

With N,N,N,N,N,N-hexamethylphosphoric triamide; sodium hydride; sodium iodide; In tetrahydrofuran; for 16h; Heating;

DOI:10.1016/S0009-3084(99)00003-1

upstream raw materials:

methanesulfonyl chloride

2,2'-[1,2-ethanediylbis(oxy)]bisethanol

Downstream raw materials:

1-N-(4'-methoxyphenyl)-1-aza-4,7,10,13-tetraoxacyclopentadecane

13-(2-methoxyphenyl)-1,4,7,10-tetraoxa-13-cyclopentadecane

N-[(S)-2-Hydroxy-3-(2-{2-[2-(2-{2-[(S)-2-hydroxy-3-(isopropyl-methanesulfonyl-amino)-propoxy]-phenoxy}-ethoxy)-ethoxy]-ethoxy}-phenoxy)-propyl]-N-isopropyl-methanesulfonamide

(S)-1-{4-[2-(2-{2-[4-((S)-2-Hydroxy-3-isopropylamino-propoxy)-phenoxy]-ethoxy}-ethoxy)-ethoxy]-phenoxy}-3-isopropylamino-propan-2-ol

Refernces

• 1、 -. "BIODEGRADABLE COMPOUND, LIPID PARTICLE, COMPOSITION COMPRISING LIPID PARTICLE, AND KIT". Paragraph 0096; 0139-0140. . Retrieved 2020/09/09.
• 2、 Stubbing, Louise A.,Kaur, Harveen,Feng, Sheryl X.,Aalderink, Miranda,Dragunow, Michael,Brimble, Margaret A.. "Synthesis of peptide homo- and heterodimers as potential mimics of platelet-derived growth factor BB". . . Retrieved 2020/07/28.