Furan, 2-butyl-5-phenyl-

Base Information

• Chemical Name: Furan, 2-butyl-5-phenyl-
• CAS No.: 80866-26-8
• Molecular Formula: C14H16O
• Molecular Weight: 200.28
• Mol file: 80866-26-8.mol

Synonyms:

Chemical Property of Furan, 2-butyl-5-phenyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Furan, 2-butyl-5-phenyl-

There total 26 articles about Furan, 2-butyl-5-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-Butylfuran (4466-24-4) + bromobenzene (108-86-1,52753-63-6) → 2-n-butyl-5-phenylfuran (80866-26-8)

Guidance literature:

With dibromo[1-(cyclobutylmethyl)-3-(methoxyethyl)benzimidazole-2-ylidene]pyridine palladium(II); potassium acetate; In N,N-dimethyl acetamide; at 130 ℃; for 1h; Reagent/catalyst; Schlenk technique; Inert atmosphere;

DOI:10.1080/00958972.2019.1692202

Reference yield: 96.0%

1-Phenyl-oct-3-yne-1,2-diol (910895-57-7) → 2-n-butyl-5-phenylfuran (80866-26-8)

Guidance literature:

With silver(I) nitrate on silica gel; In dichloromethane; at 20 ℃; for 3h;

DOI:10.1016/j.tetlet.2007.08.102

Reference yield: 95.0%

(E)-3-chloro-1-phenyloct-2-en-1-one (1415425-82-9) → 2-n-butyl-5-phenylfuran (80866-26-8)

Guidance literature:

With triethylamine; copper(l) chloride; In dichloromethane; at 23 ℃; for 18h; Inert atmosphere;

DOI:10.1021/jo302253c

upstream raw materials:

carbon monoxide

(2-butyl-2-cyclopropen-1-yl)phenylmethanone

1-phenyloct-2-yn-1-one

2-methylthio-5-n-butylfuran

Refernces

• 1、 -. "Method for preparing furan compound from brominated arone". Page/Page column 8. . Retrieved 2021/06/13.
• 2、 Kim, Hun Young,Oh, Kyungsoo. "Tandem Transformations via Friedel-Crafts Acylation Followed by a Ring-Expansion, Ring-Opening, and Cycloisomerization Sequence". . p. 696 - 699. Retrieved 2019/01/30.