2-Pentenoic acid, 3-amino-, methyl ester

Base Information

• Chemical Name: 2-Pentenoic acid, 3-amino-, methyl ester
• CAS No.: 80880-62-2
• Molecular Formula: C6H11NO2
• Molecular Weight: 129.159
• Mol file: 80880-62-2.mol

Synonyms:3-amino-4-methyl crotonic acid methylester;methyl-3-amino-pentenoate;methyl 3-aminopentenoate;methyl 3-aminopent-2-enoate;

Chemical Property of 2-Pentenoic acid, 3-amino-, methyl ester

Chemical Property:

• Boiling Point: 101-104 °C(Press: 13 Torr)
• PSA: 52.32000
• Density: 1.007±0.06 g/cm3(Predicted)
• LogP: 1.11230

Purity/Quality:

methyl3-aminopent-2-enoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Pentenoic acid, 3-amino-, methyl ester

There total 2 articles about 2-Pentenoic acid, 3-amino-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

methyl propanoyl acetate (30414-53-0) → methyl 3-aminopent-2-enoate (80880-62-2)

Guidance literature:

With ammonium acetate; In methanol; at 20 ℃; for 72h; Inert atmosphere;

DOI:10.1007/s00706-013-0962-2

Reference yield:

→ methyl 3-aminopent-2-enoate (80880-62-2)

Guidance literature:

Reference yield: 60.0%

1-phenyl-propan-1-one (93-55-0) + methyl 3-aminopent-2-enoate (80880-62-2) → methyl 6-phenyl-2-ethyl-nicotinate

Guidance literature:

With [2,2]bipyridinyl; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; copper diacetate; In N,N-dimethyl-formamide; at 120 ℃; for 20h; regioselective reaction; Sealed tube;

DOI:10.1021/acs.joc.7b01901

upstream raw materials:

methyl propanoyl acetate

Downstream raw materials:

methyl 5-cyano-2-ethyl-6-isobutyl-4-(4-methylphenyl)-1,4-dihydropyridine-3-carboxylate

5-ethyl,3-methyl 4-(4,9-dimethoxy-5-oxo-5H-furo[3,2-g]chromen-6-yl)-2-ethyl-6-phenyl-1,4-dihydropyridine-3,5-dicarboxylate

methyl 4-amino-5-methyl-1-(4-methylphenyl)-1H-pyrazole-3-carboxylate