3-(1H-Imidazol-1-yl)-6-methoxy-2,3-dihydro-4H-1-benzopyran-4-one

Base Information

Chemical Name:3-(1H-Imidazol-1-yl)-6-methoxy-2,3-dihydro-4H-1-benzopyran-4-one
CAS No.:80929-63-1
Molecular Formula:C₁₃H₁₂N₂O₃
Molecular Weight:244.25
Hs Code.:
ChEMBL ID:CHEMBL132558
DSSTox Substance ID:DTXSID50513812
Nikkaji Number:J373.134K

Synonyms:80929-63-1;3-(1H-imidazol-1-yl)-6-methoxychroman-4-one;3-(1H-imidazol-1-yl)-6-methoxy-3,4-dihydro-2H-1-benzopyran-4-one;CHEMBL132558;SCHEMBL10893708;DTXSID50513812;3-(1H-Imidazol-1-yl)-6-methoxy-2,3-dihydro-4H-1-benzopyran-4-one

Suppliers and Price of 3-(1H-Imidazol-1-yl)-6-methoxy-2,3-dihydro-4H-1-benzopyran-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 3-(1H-Imidazol-1-yl)-6-methoxy-2,3-dihydro-4H-1-benzopyran-4-one

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:244.08479225
Heavy Atom Count:18
Complexity:323

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)OCC(C2=O)N3C=CN=C3

Technology Process of 3-(1H-Imidazol-1-yl)-6-methoxy-2,3-dihydro-4H-1-benzopyran-4-one

There total 2 articles about 3-(1H-Imidazol-1-yl)-6-methoxy-2,3-dihydro-4H-1-benzopyran-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 288-32-4
1H-imidazole

: 66125-08-4
3-bromo-6-methoxy-2,3-dihydro-4H-1-benzopyran-4-one

: 59887-88-6
6-methoxy-chromen-4-one

: 80929-63-1
3-(1H-imidazol-1-yl)-6-methoxy-2,3-dihydro-4H-1-benzopyran-4-one

Guidance literature:: In N,N-dimethyl-formamide; at 60 ℃; for 5h;

Reference yield:

: 288-32-4
1H-imidazole

: 66125-08-4
3-bromo-6-methoxy-2,3-dihydro-4H-1-benzopyran-4-one

: 80929-63-1
3-(1H-imidazol-1-yl)-6-methoxy-2,3-dihydro-4H-1-benzopyran-4-one

: 89781-82-8
1,2,3,4-tetrahydro-2-(1-imidazolyl)-7-methoxy-naphthalene

Guidance literature:: With hydrogenchloride; In N,N-dimethyl-formamide;

Reference yield:

: 80929-63-1
3-(1H-imidazol-1-yl)-6-methoxy-2,3-dihydro-4H-1-benzopyran-4-one

: 344573-06-4
3-(1H-imidazol-1-yl)-4-(2,6-dichlorobenzyloxy)-6-methoxy-2,3-dihydro-4H-1-benzopyran

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / NaBH₄ / methanol / 2 h / Ambient temperature

2: 74 percent / 1.) NaH / dimethylformamide / 1.) 50 deg to room temperature; 2.) room temperature, 4 h

With sodium tetrahydroborate; sodium hydride; In methanol; N,N-dimethyl-formamide;