344573-06-4

Upstream product

• 344441-49-2 3-(1H-imidazol-1-yl)-6-methoxy-2,3-dihydro-4H-1-benzopyran-4-ol 
• 20443-98-5 2,6-Dichlorobenzyl bromide 
• 66125-08-4 3-bromo-6-methoxy-2,3-dihydro-4H-1-benzopyran-4-one 
• 80929-63-1 3-(1H-imidazol-1-yl)-6-methoxy-2,3-dihydro-4H-1-benzopyran-4-one 

Relevant academic research and scientific papers

Imidazolyl Derivatives of The Chroman Ring. 1.

The synthesis of 2-(1H-imidazol-1-yl)-2,3-dihydro-2H-1-benzopyran-4-ones (I) through 3-bromo-2,3-dihydro-4H-1-benzopyran-4-ones or more conveniently through chroman ring closure from 2-(1H-imidazol-1-yl)-2'-hydroxy-acetophenones is described.The ring closure also works well for the pyrazolyl derivatives.Compounds I and the corresponding imidazolylchromanols, -chromenes, and -chromans derived from the former, were pharmacologically investigated.