6,7-Bis(chloromethyl)-2,3-dihydro-1,4-benzodioxin

Base Information

• Chemical Name: 6,7-Bis(chloromethyl)-2,3-dihydro-1,4-benzodioxin
• CAS No.: 80985-34-8
• Molecular Formula: C₁₀H₁₀Cl₂O₂
• Molecular Weight: 233.094
• Mol file: 80985-34-8.mol

Synonyms:1,2-Bis-chlormethyl-4,5-ethylendioxy-benzol;EC-000.1437;6,7-bis-chloromethyl-1,4-benzodioxane;

Chemical Property of 6,7-Bis(chloromethyl)-2,3-dihydro-1,4-benzodioxin

Chemical Property:

• Vapor Pressure: 0.00017mmHg at 25°C
• Boiling Point: 340.4oC at 760 mmHg
• Flash Point: 136.9oC
• PSA: 18.46000
• Density: 1.341g/cm3
• LogP: 2.93540

Purity/Quality:

99% ^*data from raw suppliers

6,7-Bis(chloromethyl)-2,3-dihydro-1,4-benzodioxine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6,7-Bis(chloromethyl)-2,3-dihydro-1,4-benzodioxin

There total 2 articles about 6,7-Bis(chloromethyl)-2,3-dihydro-1,4-benzodioxin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 6-(chloromethyl)-2,3-dihydrobenzo[b][1,4]dioxine (26309-99-9) → 6,7-bis(chloromethyl)-1,4-benzodioxan (80985-34-8)

Guidance literature:

zinc(II) chloride; In acetic acid; at 50 - 75 ℃; for 0.333333h; Kinetics; other time, temperature, acid and metal chloride, ΔE(exit);

Reference yield:

→ 6,7-bis(chloromethyl)-1,4-benzodioxan (80985-34-8)

Guidance literature:

Ethylendioxy-benzol, Paraformaldehyd in Eg. im HCl-Strom bei 50grad;

DOI:10.1007/BF00918619

Reference yield: 85.0%

6,7-bis(chloromethyl)-1,4-benzodioxan (80985-34-8) + triphenylphosphine (603-35-0) → <(1,4-benzodioxan-6,7-diyl)dimethylene>bis

Guidance literature:

In toluene; for 35h; Heating;

upstream raw materials:

formaldehyd

6-(chloromethyl)-2,3-dihydrobenzo[b][1,4]dioxine

Refernces

• 1、 Lyushin, M. M.,Bacchus Yalda Pimanos. "CHLOROMETHYLATION OF 1,4-BENZODIOXANE". . p. 2427 - 2431. Retrieved 2007/10/02.