1-BroMo-2,3,4-trichlorobenzene

Base Information

• Chemical Name: 1-BroMo-2,3,4-trichlorobenzene
• CAS No.: 81067-37-0
• Molecular Formula: C6H2BrCl3
• Molecular Weight: 260.345
• Hs Code.: 2903999090
• Mol file: 81067-37-0.mol

Synonyms:2,3,4-trichlorobromobenzene;2,3,4-tri-chloro-benzonitrile;Benzonitrile,2,3,4-trichloro;

Chemical Property of 1-BroMo-2,3,4-trichlorobenzene

Chemical Property:

• PSA: 0.00000
• LogP: 4.40930

Purity/Quality:

99% ^*data from raw suppliers

1-Bromo-2,3,4-trichlorobenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: 1-Bromo-2,3,4-trichlorobenzene, is an intermediate used in different chemical synthesis. It can be used for the synthesis of monofluorinated polychlorinated biphenyls (fluoro-PCBs), for the use as internal standards for PCB analysis.

Technology Process of 1-BroMo-2,3,4-trichlorobenzene

There total 6 articles about 1-BroMo-2,3,4-trichlorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.5%

1,2,3-trichlorobenzene (87-61-6) → 1-bromo-2,3,4-trichlorobenzene (81067-37-0)

Guidance literature:

With N-Bromosuccinimide; sulfuric acid; at 10 - 30 ℃; for 0.5h; Temperature;

Reference yield:

2,3,4-trichloroaniline (634-67-3) → 1-bromo-2,3,4-trichlorobenzene (81067-37-0)

Guidance literature:

With 2-Methyl-2-nitropropane; copper(ll) bromide; In acetonitrile; at 60 ℃; for 0.5h;

DOI:10.1016/j.tet.2008.01.003

Reference yield:

1,5-dibromo-2,3,4-trichlorobenzene (811720-26-0) → 5-bromo-1,2,3-trichloro-benzene (21928-51-8) + 1-bromo-2,3,4-trichlorobenzene (81067-37-0)

Guidance literature:

1,5-dibromo-2,3,4-trichlorobenzene; With diisopropylamine; In tetrahydrofuran; hexane; at -75 ℃; for 2h;

With n-butyllithium; In tetrahydrofuran; diethyl ether; hexane; at -100 ℃; for 0.25h; Title compound not separated from byproducts;

DOI:10.1002/ejoc.200600350

upstream raw materials:

1,5-dibromo-2,3,4-trichlorobenzene

trimethyl(2,3,4-trichlorophenyl)silane

2,3,4-trichloro-1,5-phenylenebis(trimethylsilane)

1,2,3-trichlorobenzene

Downstream raw materials:

5-bromo-1,2,3-trichloro-benzene

2,4-difluoro-3-chlorobenzoic acid

3-chloro-2,4-difluorobenzonitrile

2,3,4-tri-chloro-benzonitrile

Refernces

• 1、 -. "PROCESS FOR THE PREPARATION OF 5-BROMO-1,2,3-TRICHLOROBENZENE". Page/Page column 4. . Retrieved 2016/05/24.
• 2、 Sott, Richard,Hawner, Christine,Johansen, Jon E.. "Synthesis of dioxin-like monofluorinated PCBs: for the use as internal standards for PCB analysis". . p. 4135 - 4142. Retrieved 2008/09/20.