634-67-3

Basic information

• Product Name: 2,3,4-TRICHLOROANILINE
• Synonyms: TIMTEC-BB SBB003586;2,3,4-TRICHLOROANALINE;LABOTEST-BB LT00436973;Aniline, 2,3,4-trichloro-;Trichloroaniline;2,3,4-TRICHLOROANILINE OEKANAL, 250 MG;2,3,4-Trichlorobenzenamine;(2,3,4-trichlorophenyl)amine
• CAS NO: 634-67-3
• Molecular Formula: C₆H₄Cl₃N
• Molecular Weight: 196.46
• EINECS: 211-215-6
• Product Categories: Alpha Sort;Amines;Analytical Standards;AromaticsChemical Class;Chemical Class;ChloroVolatiles/ Semivolatiles;Halogenated;TP - TZ;T-ZAlphabetic
• Mol File: 634-67-3.mol
• Article Data: 4

Chemical Properties

• Melting Point: 65-67 °C(lit.)
• Boiling Point: 292 °C774 mm Hg(lit.)
• Flash Point: 128.3°C
• Appearance: /
• Density: 1.6807 (rough estimate)
• Vapor Pressure: 0.00232mmHg at 25°C
• Refractive Index: 1.6300 (estimate)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 0.96±0.10(Predicted)
• CAS DataBase Reference: 2,3,4-TRICHLOROANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4-TRICHLOROANILINE(634-67-3)
• EPA Substance Registry System: 2,3,4-TRICHLOROANILINE(634-67-3)

Safety Data

• Hazard Codes: T,N
• Statements: 23/24/25-33-50/53
• Safety Statements: 28-36/37-45-60-61
• RIDADR: UN 2811 6.1/PG 2
• WGK Germany: 3
• Hazardous Substances Data: 634-67-3(Hazardous Substances Data)

Usage

Purification Methods

Crystallise the aniline from ligroin. The acetanilide has m 120-122o (from EtOH or *C6H6). [Beilstein 12 H 626.]

InChI:InChI=1/C6H4Cl3N/c7-3-1-2-4(10)6(9)5(3)8/h1-2H,10H2

Upstream product

• 87-61-6 1,2,3-trichlorobenzene 
• 2150-93-8 N-(3,4-dichlorophenyl)acetamide 
• 588-07-8 3-Chloroacetanilide 
• 7647-01-0 hydrogenchloride 
• 7782-50-5 chlorine 
• 108-42-9 3-chloro-aniline 
• 116278-64-9 C₁₁H₁₃Cl₂NO₂ 
• 24948-83-2 N,N-dichloroethylamine 
• 62-53-3 aniline 
• 99310-47-1 acetic acid-(2,3,4-trichloro-anilide) 
• 17700-09-3 4-nitro-1,2,3-trichlorobenzene 

Downstream Products

• 30341-47-0 1-(2,3,4-trichlorophenyl)-2-chlorobutan-3-one 
• 30359-27-4 α-chloro-β-(2,3,4-trichlorophenyl)propionaldehyde 
• 134445-30-0 4-{[(E)-2,3,4-Trichloro-phenylimino]-methyl}-benzoic acid 4-methoxy-phenyl ester 
• 33025-41-1 2,3,4,4'-tetrachlorobiphenyl 
• 55702-46-0 2,3,4-trichlorobiphenyl 
• 2112-31-4 2,3,4-tri-chloro-benzonitrile 
• 129367-41-5 [(2,3,4-Trichloro-phenylamino)-methyl]-phosphonic acid diethyl ester 
• 109825-50-5 2,4,6-trichloro-2'-t-butyl-4',6'-dinitrodiphenylamine 
• 81067-37-0 1-bromo-2,3,4-trichlorobenzene 
• 85324-93-2 2,3,4-trichlorophenyl isocyanate 
• 879-39-0 2,3,4,5-tetrachloronitrobenzene 
• 15952-70-2 2,4-difluoro-3,5-dichloro-nitrobenzene 
• 83121-15-7 3,5-dichloro-2,4-difluoro-aniline 
• 1586771-83-6 C₁₅H₁₄Cl₃NO₃ 

Relevant articles and documents

Preparation method for 3,5,-dichloro-2,4,-difluoroaniline

The invention relates to the field of organic synthesis, specifically to a preparation method for 3,5,-dichloro-2,4,-difluoroaniline and application thereof. The preparation method for 3,5,-dichloro-2,4,-difluoroaniline provided by the invention comprises the following steps: 1) nitration reaction; 2) reduction reaction; 3) diazotization reaction; 4) nitration reaction; 5) fluorination reaction; and 6) reduction reaction. The preparation method for 3,5,-dichloro-2,4,-difluoroaniline provided by the invention has the following beneficial effects: 1) the method has mild reaction conditions, is stable and controllable, has less active sites, is insusceptible to side reaction, and has good yield and quality in the whole line; and 2) raw materials are cheap and easily available, so cost can be effectively reduced, and energy is saved; meanwhile, the use of chlorine gas is avoided, so the method is environment-friendly.

Hydrolysis and Fe2+-induced Reduction of N-Aryl -O-pivaloylhydroxylamines: Aqueous Solution Chemistry of Model Carcinogens.

The N-aryl-O-pivaloylhydroxylamines, 1a-d, which serve as models for the carcinogenic metabolites of aromatic amines, decompose in aqueous media by heterolysis of the N-O bond.Substituent effects on rates of reaction and products of the decomposition of 1a-c are entirely consistent with the intermediacy of a singlet nitrenium ion.The least reactive compound in the series N-(4-nitrophenyl)-O-pivaloylhydroxylamine (1d) yields 4-nitroaniline (2d) as its major decomposition product.This material may be formed through H radical abstraction by a triplet ion, but a nitrene reaction appears to be more likely.In the presence of Fe2+ 1a-d undergo rapid reduction to the corresponding anilines 2a-d.This reaction requires complexation of the ester with Fe2+ and proceeds with heterolysis of the N-O bond since nearly quantitative yields of pivalic acid are isolated.The radical cations 25a-d appear to be the most likely precursors to the reduction products.