Technology Process of Benzenemethanol, 4-iodo-3-(methoxymethoxy)-
There total 4 articles about Benzenemethanol, 4-iodo-3-(methoxymethoxy)- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 66 percent / p-toluenesulfonic acid monohydrate, 4A molecular sieves / CH2Cl2 / 24 h / Heating
2: 96 percent / LiAlH4 / diethyl ether
3: t-BuLi, TMEDA / diethyl ether / -78 °C / without TMEDA, other solvent, temperatures and reaction times
With
lithium aluminium tetrahydride; N,N,N,N,-tetramethylethylenediamine; 4 A molecular sieve; tert.-butyl lithium; toluene-4-sulfonic acid;
In
diethyl ether; dichloromethane;
DOI:10.1016/S0040-4020(01)91921-0
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 96 percent / LiAlH4 / diethyl ether
2: t-BuLi, TMEDA / diethyl ether / -78 °C / without TMEDA, other solvent, temperatures and reaction times
With
lithium aluminium tetrahydride; N,N,N,N,-tetramethylethylenediamine; tert.-butyl lithium;
In
diethyl ether;
DOI:10.1016/S0040-4020(01)91921-0
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 98 percent / conc. H2SO4 / 5 h
2: 66 percent / p-toluenesulfonic acid monohydrate / CH2Cl2 / 24 h / Heating
3: 96 percent / LiAlH4 / diethyl ether / 0.25 h
4: 1.) t-BuLi, TMEDA, 2.) ethylene iodochloride / 1.) ether, -78 deg C, 1 h, 2.) THF
With
lithium aluminium tetrahydride; N,N,N,N,-tetramethylethylenediamine; sulfuric acid; tert.-butyl lithium; toluene-4-sulfonic acid; ethylene iodochloride;
In
diethyl ether; dichloromethane;
DOI:10.1021/jo00132a022
