2-Diazo-1,1,3,3-tetramethyl-2,3-dihydro-1H-indene

Base Information

• Chemical Name: 2-Diazo-1,1,3,3-tetramethyl-2,3-dihydro-1H-indene
• CAS No.: 81331-45-5
• Molecular Formula: C13H16N2
• Molecular Weight: 200.283
• DSSTox Substance ID: DTXSID80508392
• Nikkaji Number: J699.356G
• Wikidata: Q82365267
• Mol file: 81331-45-5.mol

Synonyms:81331-45-5;2-Diazo-1,1,3,3-tetramethyl-2,3-dihydro-1H-indene;DTXSID80508392;2-diazo-1,1,3,3-tetramethylindan

Chemical Property of 2-Diazo-1,1,3,3-tetramethyl-2,3-dihydro-1H-indene

Chemical Property:

• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 200.131348519
• Heavy Atom Count: 15
• Complexity: 295

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1(C2=CC=CC=C2C(C1=[N+]=[N-])(C)C)C

Technology Process of 2-Diazo-1,1,3,3-tetramethyl-2,3-dihydro-1H-indene

There total 1 articles about 2-Diazo-1,1,3,3-tetramethyl-2,3-dihydro-1H-indene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

1,1,3,3-tetramethyl-2-indanone triphenyl-phosphoranylidenehydrazone (74768-85-7) → 2-diazo-1,1,3,3-tetramethylindane (81331-45-5) + triphenylphosphine (603-35-0)

Guidance literature:

at 195 ℃; under 1 Torr;

DOI:10.1016/S0040-4020(01)96723-7

Reference yield: 15.0%

2,4,6-tri-(tert-butyl)thiobenzaldehyde (84543-57-7) + 2-diazo-1,1,3,3-tetramethylindane (81331-45-5) → 2,4,6-tri(tert-butyl)benzaldehyde (3975-81-3) + 3'-(2,4,6-tri-t-butylphenyl)-1,1,3,3-tetramethylspiro

Guidance literature:

With copper(l) chloride; In tetrahydrofuran; for 13.5h; Ambient temperature;

DOI:10.1246/bcsj.68.1437

Reference yield:

2-diazo-1,1,3,3-tetramethylindane (81331-45-5) + 2,4,6-Tri-tert-butylselenobenzaldehyde (107396-00-9) → C32H46Se

Guidance literature:

With copper(l) chloride; In tetrahydrofuran; at -50 ℃; for 3h;

DOI:10.1246/cl.1994.1289

upstream raw materials:

1,1,3,3-tetramethyl-2-indanone triphenyl-phosphoranylidenehydrazone

Downstream raw materials:

2,4,6-tri(tert-butyl)benzaldehyde