1-[tert-Butyl(dimethyl)silyl]-4-(prop-2-yn-1-yl)azetidin-2-one

Base Information

Chemical Name:1-[tert-Butyl(dimethyl)silyl]-4-(prop-2-yn-1-yl)azetidin-2-one
CAS No.:81355-48-8
Molecular Formula:C12H21NOSi
Molecular Weight:223.39
Hs Code.:
DSSTox Substance ID:DTXSID60535984
Nikkaji Number:J1.279.234D

Synonyms:81355-48-8;DTXSID60535984;1-[tert-Butyl(dimethyl)silyl]-4-(prop-2-yn-1-yl)azetidin-2-one

Suppliers and Price of 1-[tert-Butyl(dimethyl)silyl]-4-(prop-2-yn-1-yl)azetidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-[tert-Butyl(dimethyl)silyl]-4-(prop-2-yn-1-yl)azetidin-2-one

Chemical Property:

Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:223.139240828
Heavy Atom Count:15
Complexity:318

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)[Si](C)(C)N1C(CC1=O)CC#C

Technology Process of 1-[tert-Butyl(dimethyl)silyl]-4-(prop-2-yn-1-yl)azetidin-2-one

There total 1 articles about 1-[tert-Butyl(dimethyl)silyl]-4-(prop-2-yn-1-yl)azetidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 81355-49-9
C₁₂H₂₀LiNOSi

: 4457-32-3
4-nitrobenzyl chloroformate

: 83651-54-1
4-nitrobenzyl 1-tert-butyldimethylsilyl-4-oxo-2-azetidin-α-butynoate

: 81355-48-8
1-tert-butyldimethylsilyl-4-propargyl-2-azetidinone

Guidance literature:: In tetrahydrofuran; at -78 ℃; for 2h;
DOI:10.1248/cpb.34.1434

Reference yield: 71.0%

: 88023-78-3
para-methoxybenzyl chloride

: 81355-48-8
1-tert-butyldimethylsilyl-4-propargyl-2-azetidinone

: 266675-29-0
(rac)-1-(tert-butyldimethylsilyl)-4-{4-[(4-methoxyphenyl)methoxy]but-2-yn-1-yl}-2-azetidinone

Guidance literature:: 1-tert-butyldimethylsilyl-4-propargyl-2-azetidinone; With lithium diisopropyl amide; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

para-methoxybenzyl chloride; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 4h; Further stages.;
DOI:10.1002/(sici)1099-0690(200003)2000:6<939::aid-ejoc939>3.0.co;2-q