(4-Nitrophenyl)methyl 4-(4-oxoazetidin-2-yl)but-2-ynoate

Base Information

Chemical Name:(4-Nitrophenyl)methyl 4-(4-oxoazetidin-2-yl)but-2-ynoate
CAS No.:83651-55-2
Molecular Formula:C14H12N2O5
Molecular Weight:288.26
Hs Code.:
DSSTox Substance ID:DTXSID20535985

Synonyms:83651-55-2;(4-Nitrophenyl)methyl 4-(4-oxoazetidin-2-yl)but-2-ynoate;DTXSID20535985

Suppliers and Price of (4-Nitrophenyl)methyl 4-(4-oxoazetidin-2-yl)but-2-ynoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (4-Nitrophenyl)methyl 4-(4-oxoazetidin-2-yl)but-2-ynoate

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:288.07462149
Heavy Atom Count:21
Complexity:491

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(NC1=O)CC#CC(=O)OCC2=CC=C(C=C2)[N+](=O)[O-]

Technology Process of (4-Nitrophenyl)methyl 4-(4-oxoazetidin-2-yl)but-2-ynoate

There total 4 articles about (4-Nitrophenyl)methyl 4-(4-oxoazetidin-2-yl)but-2-ynoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 83651-54-1
4-nitrobenzyl 1-tert-butyldimethylsilyl-4-oxo-2-azetidin-α-butynoate

: 83651-55-2
4-nitrobenzyl 4-oxo-2-azetidin-α-butynoate

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; water;
DOI:10.1016/S0040-4039(00)88437-3

Reference yield:

: 4457-32-3
4-nitrobenzyl chloroformate

: 83651-55-2
4-nitrobenzyl 4-oxo-2-azetidin-α-butynoate

Guidance literature:: Multi-step reaction with 2 steps

1: 68 percent / tetrahydrofuran / 2 h / -78 °C

2: 65 percent / 10percent aq. HCl / 9 h / Ambient temperature

With hydrogenchloride; In tetrahydrofuran;
DOI:10.1248/cpb.34.1434

Reference yield:

: 81355-48-8
1-tert-butyldimethylsilyl-4-propargyl-2-azetidinone

: 83651-55-2
4-nitrobenzyl 4-oxo-2-azetidin-α-butynoate

Guidance literature:: Multi-step reaction with 2 steps

1: 68 percent / tetrahydrofuran / -78 °C

2: 65 percent / hydrogen chloride / tetrahydrofuran; H₂O

With hydrogenchloride; In tetrahydrofuran; water;
DOI:10.1016/S0040-4039(00)88437-3