Ethanimidoyl chloride, 2,2,2-trifluoro-N-hydroxy-

Base Information

• Chemical Name: Ethanimidoyl chloride, 2,2,2-trifluoro-N-hydroxy-
• CAS No.: 815-03-2
• Molecular Formula: C2HClF3NO
• Molecular Weight: 147.484
• Mol file: 815-03-2.mol

Synonyms:

Chemical Property of Ethanimidoyl chloride, 2,2,2-trifluoro-N-hydroxy-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Ethanimidoyl chloride, 2,2,2-trifluoro-N-hydroxy-

There total 1 articles about Ethanimidoyl chloride, 2,2,2-trifluoro-N-hydroxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

2,2,2-Trifluoro-O-(trifluoroacetyl)acetohydroximoyl Chloride (82817-12-7) → trifluoroacetic acid-methyl ester (431-47-0) + (trifluoroacetyl)hydroximoyl chloride (815-03-2)

Guidance literature:

With methanol; at 25 ℃;

DOI:10.1021/jo00179a031

Reference yield: 87.0%

(trifluoroacetyl)hydroximoyl chloride (815-03-2) + 4-ethynyl-1,1'-biphenyl (29079-00-3) → 5-([1,1'-biphenyl]-4-yl)-4-iodo-3-(trifluoromethyl)isoxazole

Guidance literature:

With N-iodo-succinimide; sodium hydrogencarbonate; In dichloromethane; at 20 ℃; Inert atmosphere; Schlenk technique;

DOI:10.1055/s-0035-1562115

Reference yield: 84.0%

(trifluoroacetyl)hydroximoyl chloride (815-03-2) + sodium benzylmercaptide (3492-64-6) → S-Benzyl (Z)-2,2,2-Trifluoro-N-hydroxythioacetimidate (88326-78-7)

Guidance literature:

With sodium methylate; In methanol; Ambient temperature;

DOI:10.1021/jo00179a031

upstream raw materials:

2,2,2-Trifluoro-O-(trifluoroacetyl)acetohydroximoyl Chloride

Downstream raw materials:

2,2,2-trifluoro-N'-hydroxyacetimidamide

S-Phenyl (Z)-2,2,2-trifluoro-N-hydroxythioacetimidate

S-Benzyl (Z)-2,2,2-Trifluoro-N-hydroxythioacetimidate

5-phenyl-3-(trifluoromethyl)isoxazole

Refernces