2-[(4-Fluorophenyl)sulfanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole

Base Information

Chemical Name:2-[(4-Fluorophenyl)sulfanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole
CAS No.:81527-20-0
Molecular Formula:C23H19FN2O2S
Molecular Weight:406.48
Hs Code.:
DSSTox Substance ID:DTXSID10511016
Wikidata:Q82369614

Synonyms:81527-20-0;SCHEMBL10968487;DTXSID10511016;AHPTWLVCTNZQCX-UHFFFAOYSA-N;2-[(4-Fluorophenyl)sulfanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole;4,5-bis(4-methoxyphenyl)-2-(4-fluorophenylthio)imidazole

Suppliers and Price of 2-[(4-Fluorophenyl)sulfanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-[(4-Fluorophenyl)sulfanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole

Chemical Property:

XLogP3:5.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:406.11512719
Heavy Atom Count:29
Complexity:489

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=C(N=C(N2)SC3=CC=C(C=C3)F)C4=CC=C(C=C4)OC

Technology Process of 2-[(4-Fluorophenyl)sulfanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole

There total 3 articles about 2-[(4-Fluorophenyl)sulfanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 20893-71-4
4-fluorophenyldiazonium chloride

: 39908-69-5
4,5-bis(4-methoxyphenyl)-2-mercapto-1H-imidazole

: 81527-20-0
4,5-Bis(4-methoxyphenyl)-2-(4-fluorphenylthio)-imidazol

Guidance literature:: With sodium hydroxide; copper; In N,N-dimethyl-formamide; at 20 ℃; for 3h;
DOI:10.1002/ardp.19833161108

Reference yield:

: 39908-69-5
4,5-bis(4-methoxyphenyl)-2-mercapto-1H-imidazole

: 371-40-4
4-fluoroaniline

: 81527-20-0
4,5-Bis(4-methoxyphenyl)-2-(4-fluorphenylthio)-imidazol

Guidance literature:: With hydrogenchloride; sodium hydroxide; copper; sodium nitrite; In N-methyl-acetamide;

Reference yield:

: 119-52-8
4,4'-dimethoxybenzoin

: 81527-20-0
4,5-Bis(4-methoxyphenyl)-2-(4-fluorphenylthio)-imidazol

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / dimethylformamide / 2 h / Heating

2: 38 percent / 2N NaOH, Cu / dimethylformamide / 3 h / 20 °C

With sodium hydroxide; copper; In N,N-dimethyl-formamide;
DOI:10.1002/ardp.19833161108