4-Fluoro-4'-(4-n-pentylcyclohexyl)biphenyl

Base Information

• Chemical Name: 4-Fluoro-4'-(4-n-pentylcyclohexyl)biphenyl
• CAS No.: 81793-59-1
• Molecular Formula: C₂₃H₂₉F
• Molecular Weight: 324.482
• Mol file: 81793-59-1.mol

Synonyms:4-Fluoro-4'-(4-pentylcyclohexyl)-1,1'-biphenyl;4'-Fluoro-4-(4-pentyl-cyclohexyl)-biphenyl;

Chemical Property of 4-Fluoro-4'-(4-n-pentylcyclohexyl)biphenyl

Chemical Property:

• PSA: 0.00000
• LogP: 7.34680
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

4-Fluoro-4'-(trans-4-pentylcyclohexyl)-1,1'-biphenyl 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Fluoro-4'-(4-n-pentylcyclohexyl)biphenyl

There total 3 articles about 4-Fluoro-4'-(4-n-pentylcyclohexyl)biphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-fluoroboronic acid (1765-93-1) + 1-bromo-4-(trans-4-pentylcyclohexyl)benzene (79832-89-6,153873-83-7) → 4-fluoro-4'-(4-pentylcyclohexyl)-1,1'-biphenyl (81793-59-1)

Guidance literature:

With 5%-palladium/activated carbon; potassium carbonate; In ethanol; water; at 80 ℃; for 0.5h;

DOI:10.1002/ejoc.201300334

Reference yield: 93.0%

4-fluoroboronic acid (1765-93-1) + 1-bromo-4-(4-pentylcyclohexyl)benzene (153873-83-7) → 4-fluoro-4'-(4-pentyl-cyclohexyl)-biphenyl (81793-59-1)

Guidance literature:

With potassium phosphate tribasic trihydrate; [(NC₅H₃(C(CMe)=N-2,6-(i-Pr)2C₆H₃)2)PdCl]PdCl₃; In ethanol; at 80 ℃; for 3h;

DOI:10.1016/j.jorganchem.2009.03.021

Reference yield: 78.0%

4-(trans-4-pentylcyclohexyl)phenylboronic acid + 1-Bromo-4-fluorobenzene (460-00-4) → trans-4-(4-pentyl-cyclohexyl)-4'-fluoro-1,1'-biphenyl (81793-59-1)

Guidance literature:

With pyridine; potassium phosphate; palladium dichloride; for 6h; Heating;

DOI:10.1080/00397910701397292

upstream raw materials:

4-fluoroboronic acid

1-bromo-4-(4-pentylcyclohexyl)benzene

1-bromo-4-(trans-4-pentylcyclohexyl)benzene

1-Bromo-4-fluorobenzene