Urea, N'-[[1,4-bis(phenylmethyl)-2-piperazinyl]methyl]-N,N-diethyl-

Base Information

Chemical Name:Urea, N'-[[1,4-bis(phenylmethyl)-2-piperazinyl]methyl]-N,N-diethyl-
CAS No.:819075-43-9
Molecular Formula:C24H34N4O
Molecular Weight:394.56
Hs Code.:
DSSTox Substance ID:DTXSID50458178

Synonyms:819075-43-9;Urea, N'-[[1,4-bis(phenylmethyl)-2-piperazinyl]methyl]-N,N-diethyl-;DTXSID50458178

Suppliers and Price of Urea, N'-[[1,4-bis(phenylmethyl)-2-piperazinyl]methyl]-N,N-diethyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of Urea, N'-[[1,4-bis(phenylmethyl)-2-piperazinyl]methyl]-N,N-diethyl-

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:8
Exact Mass:394.27326172
Heavy Atom Count:29
Complexity:470

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCN(CC)C(=O)NCC1CN(CCN1CC2=CC=CC=C2)CC3=CC=CC=C3

Technology Process of Urea, N'-[[1,4-bis(phenylmethyl)-2-piperazinyl]methyl]-N,N-diethyl-

There total 2 articles about Urea, N'-[[1,4-bis(phenylmethyl)-2-piperazinyl]methyl]-N,N-diethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 109-89-7
diethylamine

: 819075-19-9
1,4-dibenzyl-2-(phenoxycarbonylaminomethyl)piperazine

: 819075-43-9
1,4-dibenzyl-2-(N,N-diethylaminocarbonylaminomethyl)piperazine

Guidance literature:: for 20h; Heating;
DOI:10.1021/jm040860g

Reference yield:

: 116163-33-8,1035052-05-1,1035052-07-3
2-aminomethyl-1,4-di-phenylmethyl piperazine

: 819075-43-9
1,4-dibenzyl-2-(N,N-diethylaminocarbonylaminomethyl)piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: 86.8 percent / pyridine / CH₂Cl₂ / 4 h / 0 - 20 °C

2: 61 percent / 20 h / Heating

With pyridine; In dichloromethane;
DOI:10.1021/jm040860g

Reference yield:

: 819075-43-9
1,4-dibenzyl-2-(N,N-diethylaminocarbonylaminomethyl)piperazine

: 3-[1,4-bis-(3,4,5-trimethoxy-benzoyl)-piperazin-2-ylmethyl]-1,1-diethyl-urea

Guidance literature:: Multi-step reaction with 2 steps

1: 35 percent / H₂; aq. HCl / Pd/C / 40 °C

2: 81 percent / Et₃N / CH₂Cl₂ / 20 °C

With hydrogenchloride; hydrogen; triethylamine; palladium on activated charcoal; In dichloromethane;
DOI:10.1021/jm040860g