1H-Benzimidazole-5-carboxamide, 2-(4-nitrophenyl)-N-phenyl-

Base Information

Chemical Name:1H-Benzimidazole-5-carboxamide, 2-(4-nitrophenyl)-N-phenyl-
CAS No.:820242-65-7
Molecular Formula:C20H14N4O3
Molecular Weight:358.356
Hs Code.:
DSSTox Substance ID:DTXSID70460359

Synonyms:820242-65-7;1H-Benzimidazole-5-carboxamide, 2-(4-nitrophenyl)-N-phenyl-;SCHEMBL19994539;DTXSID70460359

Suppliers and Price of 1H-Benzimidazole-5-carboxamide, 2-(4-nitrophenyl)-N-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1H-Benzimidazole-5-carboxamide, 2-(4-nitrophenyl)-N-phenyl-

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:358.10659032
Heavy Atom Count:27
Complexity:538

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)NC(=O)C2=CC3=C(C=C2)N=C(N3)C4=CC=C(C=C4)[N+](=O)[O-]

Technology Process of 1H-Benzimidazole-5-carboxamide, 2-(4-nitrophenyl)-N-phenyl-

There total 4 articles about 1H-Benzimidazole-5-carboxamide, 2-(4-nitrophenyl)-N-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 62-53-3
aniline

: 69570-99-6
2-(4-nitrophenyl)-1H-benzimidazole-5-carboxylic acid

: 820242-65-7
2-(4-nitro-phenyl)-1H-benzoimidazole-5-carboxylic acid phenylamide

Guidance literature:: 2-(4-nitrophenyl)-1H-benzimidazole-5-carboxylic acid; In N,N-dimethyl-formamide; for 3h;

aniline; With dmap; In N,N-dimethyl-formamide; for 18h;
DOI:10.1021/jm049288j

Reference yield:

: 98-88-4
benzoyl chloride

: 69570-99-6
2-(4-nitrophenyl)-1H-benzimidazole-5-carboxylic acid

: 820242-65-7
2-(4-nitro-phenyl)-1H-benzoimidazole-5-carboxylic acid phenylamide

Guidance literature:: 2-(4-nitrophenyl)-1H-benzimidazole-5-carboxylic acid; With 1,1'-carbonyldiimidazole; In N,N-dimethyl-formamide; at 80 ℃; for 3h;

benzoyl chloride; In N,N-dimethyl-formamide; for 18h; Heating;
DOI:10.1016/j.ejmech.2006.03.014

Reference yield:

: 555-16-8
4-nitrobenzaldehdye

: 820242-65-7
2-(4-nitro-phenyl)-1H-benzoimidazole-5-carboxylic acid phenylamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: 55 percent / nitrobenzene / 18 h / 155 - 160 °C

2.1: 1,1'-carbonyldiimidazole / dimethylformamide / 3 h / 80 °C

2.2: dimethylformamide / 18 h / Heating

With 1,1'-carbonyldiimidazole; In nitrobenzene; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2006.03.014