2-Butoxy-1,3,2-dioxaphospholane 2-oxide

Base Information

• Chemical Name: 2-Butoxy-1,3,2-dioxaphospholane 2-oxide
• CAS No.: 67554-09-0
• Molecular Formula: C6H13O4P
• Molecular Weight: 180.141
• European Community (EC) Number: 266-716-2
• DSSTox Substance ID: DTXSID5070498
• Nikkaji Number: J310.264E
• Wikidata: Q81997823
• Mol file: 67554-09-0.mol

Synonyms:2-Butoxy-1,3,2-dioxaphospholane 2-oxide;67554-09-0;1,3,2-Dioxaphospholane, 2-butoxy-, 2-oxide;EINECS 266-716-2;SCHEMBL8736107;DTXSID5070498;C6-H13-O4-P

Chemical Property of 2-Butoxy-1,3,2-dioxaphospholane 2-oxide

Chemical Property:

• Vapor Pressure: 0.172mmHg at 25°C
• Boiling Point: 220°Cat760mmHg
• Flash Point: 101°C
• PSA: 54.57000
• Density: 1.16g/cm³
• LogP: 1.95800
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 180.05514589
• Heavy Atom Count: 11
• Complexity: 149

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCOP1(=O)OCCO1

Technology Process of 2-Butoxy-1,3,2-dioxaphospholane 2-oxide

There total 2 articles about 2-Butoxy-1,3,2-dioxaphospholane 2-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

2-Chloro-2-oxo-1,3,2-dioxaphospholane (6609-64-9) + butan-1-ol (71-36-3) → 2-butoxy-1,3,2-dioxaphospholane 2-oxide (67554-09-0)

Guidance literature:

butan-1-ol; With triethylamine; In tetrahydrofuran; for 0.5h; Cooling with ice;

2-Chloro-2-oxo-1,3,2-dioxaphospholane; In tetrahydrofuran; at 20 ℃; for 5h; Cooling with ice;

Reference yield:

→ 2-butoxy-1,3,2-dioxaphospholane 2-oxide (67554-09-0)

Guidance literature:

entspr. Phosphit, Oxidation;

DOI:10.1016/0032-3950(61)90167-8

upstream raw materials:

2-Chloro-2-oxo-1,3,2-dioxaphospholane

butan-1-ol