3-(Bromomethyl)-5-fluoro-2-[(4-fluorophenyl)sulfanyl]-1-benzothiophene

Base Information

Chemical Name:3-(Bromomethyl)-5-fluoro-2-[(4-fluorophenyl)sulfanyl]-1-benzothiophene
CAS No.:820975-37-9
Molecular Formula:C15H9BrF2S2
Molecular Weight:371.269
Hs Code.:
DSSTox Substance ID:DTXSID80692841
Wikidata:Q82621877

Synonyms:820975-37-9;3-(Bromomethyl)-5-fluoro-2-[(4-fluorophenyl)sulfanyl]-1-benzothiophene;SCHEMBL6502619;DTXSID80692841

Suppliers and Price of 3-(Bromomethyl)-5-fluoro-2-[(4-fluorophenyl)sulfanyl]-1-benzothiophene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 3-(Bromomethyl)-5-fluoro-2-[(4-fluorophenyl)sulfanyl]-1-benzothiophene

Chemical Property:

XLogP3:6.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:369.92971
Heavy Atom Count:20
Complexity:323

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1F)SC2=C(C3=C(S2)C=CC(=C3)F)CBr

Technology Process of 3-(Bromomethyl)-5-fluoro-2-[(4-fluorophenyl)sulfanyl]-1-benzothiophene

There total 3 articles about 3-(Bromomethyl)-5-fluoro-2-[(4-fluorophenyl)sulfanyl]-1-benzothiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 820975-38-0
5-fluoro-2-(4-fluorophenylthio)-3-methylbenzo[b]thiophene

: 820975-37-9
3-(bromomethyl)-5-fluoro-2-(4-fluorophenylthio)benzo[b]thiophene

Guidance literature:: With N-Bromosuccinimide; dibenzoyl peroxide; In tetrachloromethane; for 4h; Reflux; Irradiation;
DOI:10.1016/j.ejmech.2011.02.044

Reference yield:

: 2968-13-0
1-(4-fluoro-phenylsulfanyl)propan-2-one

: 820975-37-9
3-(bromomethyl)-5-fluoro-2-(4-fluorophenylthio)benzo[b]thiophene

Guidance literature:: Multi-step reaction with 2 steps

1: polyphosphoric acid / 1 h / 80 °C

2: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 4 h / Reflux; Irradiation

With N-Bromosuccinimide; dibenzoyl peroxide; In tetrachloromethane;
DOI:10.1016/j.ejmech.2011.02.044

Reference yield:

: 371-42-6
4-Fluorothiophenol

: 820975-37-9
3-(bromomethyl)-5-fluoro-2-(4-fluorophenylthio)benzo[b]thiophene

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydroxide / water / 1 h / 0 °C

2: polyphosphoric acid / 1 h / 80 °C

3: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 4 h / Reflux; Irradiation

With N-Bromosuccinimide; sodium hydroxide; dibenzoyl peroxide; In tetrachloromethane; water;
DOI:10.1016/j.ejmech.2011.02.044