5-Fluoro-2-[(4-fluorophenyl)sulfanyl]-3-methyl-1-benzothiophene

Base Information

Chemical Name:5-Fluoro-2-[(4-fluorophenyl)sulfanyl]-3-methyl-1-benzothiophene
CAS No.:820975-38-0
Molecular Formula:C15H10F2S2
Molecular Weight:292.373
Hs Code.:
DSSTox Substance ID:DTXSID20692840
Wikidata:Q82621876

Synonyms:820975-38-0;5-Fluoro-2-[(4-fluorophenyl)sulfanyl]-3-methyl-1-benzothiophene;SCHEMBL6505648;DTXSID20692840

Suppliers and Price of 5-Fluoro-2-[(4-fluorophenyl)sulfanyl]-3-methyl-1-benzothiophene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 5-Fluoro-2-[(4-fluorophenyl)sulfanyl]-3-methyl-1-benzothiophene

Chemical Property:

XLogP3:5.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:292.01919899
Heavy Atom Count:19
Complexity:305

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(SC2=C1C=C(C=C2)F)SC3=CC=C(C=C3)F

Technology Process of 5-Fluoro-2-[(4-fluorophenyl)sulfanyl]-3-methyl-1-benzothiophene

There total 1 articles about 5-Fluoro-2-[(4-fluorophenyl)sulfanyl]-3-methyl-1-benzothiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 2968-13-0
1-(4-fluoro-phenylsulfanyl)propan-2-one

: 820975-38-0
5-fluoro-2-(4-fluorophenylthio)-3-methylbenzo[b]thiophene

Guidance literature:: With polyphosphoric acid; at 80 ℃; for 1h;
DOI:10.1016/j.ejmech.2011.02.044

Reference yield: 60.0%

: 820975-38-0
5-fluoro-2-(4-fluorophenylthio)-3-methylbenzo[b]thiophene

: 820975-37-9
3-(bromomethyl)-5-fluoro-2-(4-fluorophenylthio)benzo[b]thiophene

Guidance literature:: With N-Bromosuccinimide; dibenzoyl peroxide; In tetrachloromethane; for 4h; Reflux; Irradiation;
DOI:10.1016/j.ejmech.2011.02.044

Reference yield:

: 820975-38-0
5-fluoro-2-(4-fluorophenylthio)-3-methylbenzo[b]thiophene

: 820975-39-1
2-(5-fluoro-2-(4-fluorophenylthio)benzo[b]thiophen-3-yl)acetonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 4 h / Reflux; Irradiation

2: dimethyl sulfoxide / 1 h / 20 °C

With N-Bromosuccinimide; dibenzoyl peroxide; In tetrachloromethane; dimethyl sulfoxide;
DOI:10.1016/j.ejmech.2011.02.044