9-Methylfluorene-9-carbonyl chloride

Base Information

• Chemical Name: 9-Methylfluorene-9-carbonyl chloride
• CAS No.: 82102-37-2
• Molecular Formula: C15H11ClO
• Molecular Weight: 242.705
• Hs Code.: 2916399090
• Mol file: 82102-37-2.mol

Synonyms:9-methyl-9-fluorenonyl chloride;9-methyl-9Hfluorene-9-carbonyl chloride;9H-Fluorene-9-carbonyl chloride,9-methyl;9-methylfluorene-9-carboxylic acid chloride;9-methyl-fluorene-9-carbonyl chloride;

Chemical Property of 9-Methylfluorene-9-carbonyl chloride

Chemical Property:

• Flash Point: >110℃
• PSA: 17.07000
• LogP: 3.73840

Purity/Quality:

98%min ^*data from raw suppliers

9-Methylfluorene-9-carbonylChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): 5266487
• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 9-Methylfluorene-9-carbonyl chloride

There total 6 articles about 9-Methylfluorene-9-carbonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

9-methylfluorene-9-carboxylic acid (3300-17-2) → 9-methyl-9H-fluorene-9-carbonyl chloride (82102-37-2)

Guidance literature:

With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 30 ℃;

DOI:10.1002/jlcr.2962

Reference yield:

9-methylfluorene (2523-37-7) → 9-methyl-9H-fluorene-9-carbonyl chloride (82102-37-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / -78 °C / Inert atmosphere

1.2: -78 - 20 °C

2.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 3 h / 30 °C / Inert atmosphere

With n-butyllithium; oxalyl dichloride; N,N-dimethyl-formamide; In tetrahydrofuran; hexane; dichloromethane;

DOI:10.1021/ja200818w

Reference yield:

9-methyl-9H-fluoren-9-ol (6311-22-4) → 9-methyl-9H-fluorene-9-carbonyl chloride (82102-37-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: acetic acid / Reflux

1.2: 760.05 Torr

2.1: n-butyllithium / hexane; tetrahydrofuran / 0.17 h / -78 °C / Inert atmosphere

2.2: 20 °C

3.1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 3 h / 30 °C / Inert atmosphere

With n-butyllithium; oxalyl dichloride; acetic acid; N,N-dimethyl-formamide; In tetrahydrofuran; hexane; dichloromethane;

upstream raw materials:

9-methylfluorene-9-carboxylic acid

9-methylfluorene

9-methyl-9H-fluoren-9-ol

9-fluorenone

Downstream raw materials:

9-methylene-fluorene

(E)-3-phenyl-1-(4'-(tetrahydro-2H-pyran-4''-yloxy)phenyl)prop-2-en-1-one

3-phenyl-1-(3',4',5'-trimethoxyphenyl)propan-1-one

(E)-1-(3-methoxyphenyl)-3-phenylprop-2-en-1-one

Refernces

• 1、 Febles, Martín,Montalv?o, Sofía,Crespín, Guillermo Díaz,Norte, Manuel,Padrón, José M.,Tammela, P?ivi,Fernández, José J.,Daranas, Antonio Hernández. "Synthesis and biological evaluation of crown ether acyl derivatives". supporting information. p. 5591 - 5593. Retrieved 2016/11/09.
• 2、 -. "SYSTEM PROVIDING CONTROLLED DELIVERY OF GASEOUS CO FOR CARBONYLATION REACTIONS". Page/Page column 85. . Retrieved 2012/06/30.