4-(2,6-Dichlorophenyl)piperidine

Base Information

• Chemical Name: 4-(2,6-Dichlorophenyl)piperidine
• CAS No.: 82211-90-3
• Molecular Formula: C11H13Cl2N
• Molecular Weight: 230.137
• DSSTox Substance ID: DTXSID30468679
• Nikkaji Number: J3.608.178C
• Wikidata: Q72467624
• Mol file: 82211-90-3.mol

Synonyms:4-(2,6-dichlorophenyl)piperidine;82211-90-3;Piperidine, 4-(2,6-dichlorophenyl)-;SCHEMBL4520760;DTXSID30468679;SZSOOIJVCGFMHM-UHFFFAOYSA-N;4-(2,6-dichloro-phenyl)-piperidine;AKOS012457691;EN300-214900

Chemical Property of 4-(2,6-Dichlorophenyl)piperidine

Chemical Property:

• Melting Point: 210-215℃
• Boiling Point: 291℃
• Flash Point: 130℃
• PSA: 12.03000
• Density: 1.207
• LogP: 3.78920
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 229.0425048
• Heavy Atom Count: 14
• Complexity: 170

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CNCCC1C2=C(C=CC=C2Cl)Cl

Technology Process of 4-(2,6-Dichlorophenyl)piperidine

There total 1 articles about 4-(2,6-Dichlorophenyl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

4-(2,6-dichlorophenyl)piperidine-2,6-dione (371981-22-5) → 4-(2,6-dichlorophenyl)piperidine (82211-90-3)

Guidance literature:

4-(2,6-dichlorophenyl)piperidine-2,6-dione; With dimethylsulfide borane complex; In tetrahydrofuran; at 0 ℃; Inert atmosphere; Reflux;

With hydrogenchloride; In tetrahydrofuran; water; at 0 ℃; Inert atmosphere; Reflux;

With sodium hydroxide; In tetrahydrofuran; water; at 0 ℃;

DOI:10.1016/j.bmc.2009.05.068

Reference yield: 94.0%

4-(2,6-dichlorophenyl)piperidine (82211-90-3) + 3-bromopropylamine tert-butylcarbamate (83948-53-2) → C19H28Cl2N2O2 (1206532-62-8)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 1h;

DOI:10.1016/j.bmc.2009.05.068

Reference yield: 5.0%

4-(2,6-dichlorophenyl)piperidine (82211-90-3) + (±)-6-methyl-12-oxatricyclo[8.2.1.02,7]trideca-2,4,6-trien-11-ol → (±)-cis-7-{[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl}-1-methyl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ol (371980-95-9,371980-98-2) + (±)-cis-7-(hydroxymethyl)-1-methyl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ol

Guidance literature:

4-(2,6-dichlorophenyl)piperidine; (±)-6-methyl-12-oxatricyclo[8.2.1.02,7]trideca-2,4,6-trien-11-ol; In methanol; at 50 ℃; for 2h;

With sodium tetrahydroborate; at 0 - 20 ℃; for 16h; Concentration; Reagent/catalyst; Solvent; Time; Temperature;

DOI:10.1055/s-0036-1588379

upstream raw materials:

4-(2,6-dichlorophenyl)piperidine-2,6-dione

Downstream raw materials:

2-[4-(2,6-dichloro-phenyl)-piperidin-1-ylmethyl]-3-methyl-1H-indole

3-[4-(2,6-dichloro-phenyl)-piperidin-1-ylmethyl]-1H-indole-2-carboxylic acid ethyl ester

C₁₉H₂₈Cl₂N₂O₂

4-(2,6-dichloro-phenyl)-1-(indole-2-carbonyl)-piperidine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 82211-90-3 4-(2,6-dichlorophenyl)piperidine

Send

Send

Metric Ton KG G Pound L ML

Send

Send